DRSC/TRiP Functional Genomics Resources

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Protein Alignment E(spl)mgamma-HLH and hes2.2

DIOPT Version :9

Sequence 1:NP_524504.2 Gene:E(spl)mgamma-HLH / 43151 FlyBaseID:FBgn0002735 Length:205 Species:Drosophila melanogaster
Sequence 2:NP_001038818.1 Gene:hes2.2 / 751634 ZFINID:ZDB-GENE-060825-55 Length:172 Species:Danio rerio


Alignment Length:196 Identity:59/196 - (30%)
Similarity:82/196 - (41%) Gaps:34/196 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 QYRKVMKPMLERKRRARINKCLDELKDLMVATLESEGEHVTRLEKADILELTVTHLQKMKQQRQH 78
            :.||.:||:||:|||||||..||.||.|::.....:....::||||||||:||..|.        
Zfish     7 ELRKTLKPLLEKKRRARINDSLDRLKALILPLTGKDNCRYSKLEKADILEMTVRFLT-------- 63

  Fly    79 KRASGDESLTP----AEGFRSGYIHAVNEVSRSLSQLPGMNVSLGTQLMTHLGQRLNQIQPAEKE 139
                 |...||    |..|..||...:..||..|.|         |.|......|:|..  .::.
Zfish    64 -----DIQTTPSKDTAVSFTEGYTTCLQRVSARLPQ---------TSLDAETRHRVNDF--IQRS 112

  Fly   140 VLPVTAPLSVHIANRDAYSVPISPISSYAGSPNSNTSSTSHSLLTTIDVTKMEDDSEDEENVWRP 204
            |:|.|.      |.::..:.....:|.......:..||:|.|.....|:....:.......||||
Zfish   113 VMPKTP------ACQNCCAQSSRMMSQIQQKLQNLKSSSSRSTNPKQDILSRPEPVPLITEVWRP 171

  Fly   205 W 205
            |
Zfish   172 W 172

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
E(spl)mgamma-HLHNP_524504.2 HLH 15..77 CDD:238036 29/61 (48%)
ORANGE 91..135 CDD:128787 11/43 (26%)
hes2.2NP_001038818.1 HLH 6..67 CDD:238036 30/72 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170573786
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4304
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000785
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10985
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
54.840

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