Protein Alignment E(spl)mgamma-HLH and hes1

DIOPT Version :9

• Sequence 1: NP_524504.2
• Gene: E(spl)mgamma-HLH / 43151
• FlyBaseID: FBgn0002735
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_001011194.1
• Gene: hes1 / 496617
• XenbaseID: XB-GENE-487995
• Length: 267
• Species: Xenopus tropicalis
• Alignment Length: 254
• Identity: 69/254 - (27%)
• Similarity: 112/254 - (44%)
• Gaps: 81/254 - (31%)

  Fly    14 QYRKVMKPMLERKRRARINKCLDELKDLMVATLESEGEHVTRLEKADILELTVTHLQKMKQQRQH 78
            ::||..||::|::||||||:.|.:||.|::..|:.:....::||||||||:||.||:.:::.:..
 Frog    33 EHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRVQMT 97

  Fly    79 KRASGDESLTPAEGFRSGYIHAVNEVSRSLSQLPGMNVSLGTQLMTHLGQRLNQIQ----PAEKE 139
            ...|.|.|:...  :|:|:...:|||:|.||...|:|..:.|:|:.||...:|||.    |.:.:
 Frog    98 AALSTDPSVLGK--YRAGFSECMNEVTRFLSTCEGVNTDVRTRLLGHLANCMNQINAMNYPTQPQ 160

  Fly   140 VLPVTAPLSVHIANRDAYSVPI------------SPISSYAGSP--------------------- 171
            :....||       ..||..|:            :||:...|.|
 Frog   161 IPAAAAP-------HPAYGQPLVQLQGAAPQSSPAPIACKMGGPPVEAAKVYGGFQLVPAPDGQF 218

  Fly   172 --------------------NSNTS-----STSHSLLTTIDVTKMEDDSEDEENVWRPW 205
                                |||..     |.|.|::.::..          ::|||||
 Frog   219 AFLITNPAFPHNGSVIPVYTNSNVGTALPPSVSPSVMPSVTA----------DSVWRPW 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mgamma-HLH	NP_524504.2	HLH	15..77	CDD:238036	28/61 (46%)
		ORANGE	91..135	CDD:128787	17/47 (36%)
hes1	NP_001011194.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		5/11 (45%)
		bHLH-O_HES1_4	33..95	CDD:381465	28/61 (46%)
		Hairy_orange	110..148	CDD:369405	14/37 (38%)
		WRPW motif. /evidence=ECO:0000255	264..267		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010