Protein Alignment E(spl)mgamma-HLH and hes4

DIOPT Version :9

• Sequence 1: NP_524504.2
• Gene: E(spl)mgamma-HLH / 43151
• FlyBaseID: FBgn0002735
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_988870.1
• Gene: hes4 / 394465
• XenbaseID: XB-GENE-487830
• Length: 281
• Species: Xenopus tropicalis
• Alignment Length: 265
• Identity: 78/265 - (29%)
• Similarity: 124/265 - (46%)
• Gaps: 64/265 - (24%)

  Fly     2 SSLQMSEMSKT-YQYRKVMKPMLERKRRARINKCLDELKDLMVATLESEGEHVTRLEKADILELT 65
            ||.|..:..|: .::||..||::|::||||||:.|.:||.|::..|:.:....::||||||||:|
 Frog    20 SSAQTPDKPKSASEHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMT 84

  Fly    66 VTHLQKMKQQRQHKRASGDESLTPAEGFRSGYIHAVNEVSRSLSQLPGMNVSLGTQLMTHLGQRL 130
            |.||:.:::.:.....:.|.|:...  :|:|:...:|||:|.||...|:|..:.|:|:.||...|
 Frog    85 VKHLRNLQRVQMTAALTADPSVLGK--YRAGFNECMNEVTRFLSTCEGVNTEVRTRLLGHLSSCL 147

  Fly   131 NQI-------QPAEKEVL--------PVTAPLSVHIANRDAYS----------VP--------IS 162
            .||       .|:.::.|        |...|:...:...:|.|          ||        :.
 Frog   148 GQIVAMNYQQPPSSQQPLHVQLPSSTPAPVPMPCKVNPAEAISPKVFQGGFQLVPATDGQFAFLI 212

  Fly   163 PISSYAGSPN------SNTSSTSH---------SLLTTIDVTKM------------EDDSEDEEN 200
            |..:|..||.      :||:.||.         ..|||.. .||            ...::..|:
 Frog   213 PNPAYTTSPGPVIPLYANTNVTSPGGPQSQSPVQGLTTFG-HKMPHMAQAVSPLGGSTGADSAES 276

  Fly   201 VWRPW 205
            |||||
 Frog   277 VWRPW 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mgamma-HLH	NP_524504.2	HLH	15..77	CDD:238036	28/61 (46%)
		ORANGE	91..135	CDD:128787	17/50 (34%)
hes4	NP_988870.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..44		8/23 (35%)
		bHLH-O_HES1_4	33..95	CDD:381465	28/61 (46%)
		Hairy_orange	110..147	CDD:369405	14/36 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..281		4/18 (22%)
		WRPW motif. /evidence=ECO:0000255	278..281		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010