Protein Alignment E(spl)mgamma-HLH and her8a

DIOPT Version :9

• Sequence 1: NP_524504.2
• Gene: E(spl)mgamma-HLH / 43151
• FlyBaseID: FBgn0002735
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_955918.3
• Gene: her8a / 323656
• ZFINID: ZDB-GENE-030131-2376
• Length: 221
• Species: Danio rerio
• Alignment Length: 227
• Identity: 71/227 - (31%)
• Similarity: 106/227 - (46%)
• Gaps: 62/227 - (27%)

  Fly    16 RKVMKPMLERKRRARINKCLDELKDLMVATLESEGEHVTRLEKADILELTVTHLQKMKQQRQHKR 80
            ||:.||::|:|||.|||..|::||.:||   ::.....::|||||:||:||.|::.:  ||.|.:
Zfish    20 RKLRKPLIEKKRRERINSSLEQLKGIMV---DAYNLDQSKLEKADVLEITVQHMENL--QRGHGQ 79

  Fly    81 ASGDESLTPAEGFR------SGYIHAVNEVSRSLSQLPGMNVSLGTQLMTHLGQRLNQI--QPAE 137
            ..   |.:|..||.      ||||..::||...|...|||:.:||.:|:.||.:.|..|  :|:.
Zfish    80 GG---SNSPGTGFESRQRYSSGYIQCMHEVHNLLLSCPGMDKTLGARLLNHLLKSLPHISTEPSG 141

  Fly   138 KEVLPVTAPLSVHIANRDAYSVPISPISSYAGSPN-----------SNTSSTSHSLLTTIDVTKM 191
            ......::||            |:||..|....|:           |..||.:|||     |...
Zfish   142 TSSAGTSSPL------------PLSPTQSPINLPSSLQPHALLLSPSPPSSPTHSL-----VRPR 189

  Fly   192 EDDSED------------------EENVWRPW 205
            |..|..                  :.::||||
Zfish   190 EQSSPPSSPSPQSPASLPPFFPGVDPSMWRPW 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mgamma-HLH	NP_524504.2	HLH	15..77	CDD:238036	27/60 (45%)
		ORANGE	91..135	CDD:128787	19/51 (37%)
her8a	NP_955918.3	HLH	17..75	CDD:238036	26/59 (44%)
		Hairy_orange	95..133	CDD:284859	15/37 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573649
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I5073
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1483774at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.860