Protein Alignment E(spl)mgamma-HLH and Hes1

DIOPT Version :9

• Sequence 1: NP_524504.2
• Gene: E(spl)mgamma-HLH / 43151
• FlyBaseID: FBgn0002735
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_077336.3
• Gene: Hes1 / 29577
• RGDID: 62081
• Length: 281
• Species: Rattus norvegicus
• Alignment Length: 263
• Identity: 68/263 - (25%)
• Similarity: 113/263 - (42%)
• Gaps: 87/263 - (33%)

  Fly    14 QYRKVMKPMLERKRRARINKCLDELKDLMVATLESEGEHVTRLEKADILELTVTHLQKMKQQRQH 78
            ::||..||::|::||||||:.|.:||.|::..|:.:....::||||||||:||.||:.:::.:..
  Rat    33 EHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMT 97

  Fly    79 KRASGDESLTPAEGFRSGYIHAVNEVSRSLSQLPGMNVSLGTQLMTHLGQRLNQIQ--------- 134
            ...|.|.|:...  :|:|:...:|||:|.||...|:|..:.|:|:.||...:.||.
  Rat    98 AALSTDPSVLGK--YRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMTYPGQAH 160

  Fly   135 -------------------------------PAEKEVLPVTAPLSVH------------------ 150
                                           |......|.:||..:.
  Rat   161 PALQAPPPPPPSGPGGPQHAPFAPPPPLVPIPGGAAPPPGSAPCKLGSQAGEAAKVFGGFQVVPA 225

  Fly   151 --------IAN-RDAYSVPISPI-SSYAGS---PNSNTSSTSHSLLTTIDVTKMEDDSEDEENVW 202
                    |.| ..|:|.|:.|: :|.:|:   ||:.:.|:..||..              :::|
  Rat   226 PDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVGPNAVSPSSGSSLTA--------------DSMW 276

  Fly   203 RPW 205
            |||
  Rat   277 RPW 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mgamma-HLH	NP_524504.2	HLH	15..77	CDD:238036	28/61 (46%)
		ORANGE	91..135	CDD:128787	16/83 (19%)
Hes1	NP_077336.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..44		4/10 (40%)
		bHLH-O_HES1_4	33..95	CDD:381465	28/61 (46%)
		Hairy_orange	110..148	CDD:400076	14/37 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	158..206		4/47 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..281		9/39 (23%)
		WRPW motif	276..279		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334582
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840