DRSC/TRiP Functional Genomics Resources

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Protein Alignment E(spl)mgamma-HLH and Hey1

DIOPT Version :9

Sequence 1:NP_524504.2 Gene:E(spl)mgamma-HLH / 43151 FlyBaseID:FBgn0002735 Length:205 Species:Drosophila melanogaster
Sequence 2:NP_034553.2 Gene:Hey1 / 15213 MGIID:1341800 Length:299 Species:Mus musculus


Alignment Length:128 Identity:42/128 - (32%)
Similarity:71/128 - (55%) Gaps:16/128 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 RKVMKPMLERKRRARINKCLDELKDLMVATLESEGEHVTRLEKADILELTVTHLQKMKQQRQHKR 80
            ||..:.::|::||.|||..|.||:.|:.:..|.:|.  .:||||:||::||.||:.:       .
Mouse    50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKML-------H 105

  Fly    81 ASGDESLTPAEG----FRS-GYIHAVNEVSRSLSQLPGMNVS--LGTQLMTHLGQRLNQIQPA 136
            .:|.:....|..    :|| |:...:.||:|.||.:.|::.|  |..:|::||....:|.:.|
Mouse   106 TAGGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREAA 168

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
E(spl)mgamma-HLHNP_524504.2 HLH 15..77 CDD:238036 24/60 (40%)
ORANGE 91..135 CDD:128787 15/50 (30%)
Hey1NP_034553.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..53 2/2 (100%)
Transcriptional repression and interaction with NCOR1 and SIN3A. /evidence=ECO:0000250 48..117 26/75 (35%)
HLH 50..107 CDD:238036 24/65 (37%)
ORANGE 120..166 CDD:128787 15/45 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 194..234
YRPW motif 289..292
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167830842
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4304
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.740

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