Protein Alignment E(spl)mgamma-HLH and Hes5

DIOPT Version :9

• Sequence 1: NP_524504.2
• Gene: E(spl)mgamma-HLH / 43151
• FlyBaseID: FBgn0002735
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: XP_006538625.3
• Gene: Hes5 / 15208
• MGIID: 104876
• Length: 415
• Species: Mus musculus
• Alignment Length: 230
• Identity: 51/230 - (22%)
• Similarity: 90/230 - (39%)
• Gaps: 73/230 - (31%)

  Fly     8 EMSKTYQYRKVMKPMLERKRRARINKCLDELKDLMVATLESE-GEHV--TRLEKADILELTVTHL 69
            ||....:..::.||::|:.||.|||..:::||.|    ||.| ..|.  ::||||||||:.|::|
Mouse   227 EMLSPKEKNRLRKPVVEKMRRDRINSSIEQLKLL----LEQEFARHQPNSKLEKADILEMAVSYL 287

  Fly    70 QKMKQQ---------------------------RQHKRASGDESLTPAEGFRSGYIHAVNEVSRS 107
            :..|.:                           .....|:|.:||  .:.:..||...:.|..:.
Mouse   288 KHSKGEPGACARLLLPADVAPTARAPLMPLRLPTAFAAAAGPKSL--HQDYSEGYSWCLQEAVQF 350

  Fly   108 LSQLPGMNVSLGTQ--LMTHLGQRLNQIQPAEKEVLPVTAPLSVHIANRDAYSVPISPISSYAGS 170
            |:    ::.:..||  |:.|..:......||::...|..||                       .
Mouse   351 LT----LHAASDTQMKLLYHFQRPPAPAAPAKEPPAPGAAP-----------------------Q 388

  Fly   171 PNSNTSSTSHSLLTTIDVTKMEDDSEDEENVWRPW 205
            |..:::..:.:.::|        ..:....:||||
Mouse   389 PARSSAKAAAAAVST--------SRQPACGLWRPW 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mgamma-HLH	NP_524504.2	HLH	15..77	CDD:238036	26/91 (29%)
		ORANGE	91..135	CDD:128787	8/45 (18%)
Hes5	XP_006538625.3	bHLH-O_HES5	236..292	CDD:381467	25/59 (42%)
		ORANGE	334..369	CDD:128787	8/38 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830906
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1011
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840