Protein Alignment E(spl)mgamma-HLH and Hes2

DIOPT Version :9

• Sequence 1: NP_524504.2
• Gene: E(spl)mgamma-HLH / 43151
• FlyBaseID: FBgn0002735
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_001288734.1
• Gene: Hes2 / 15206
• MGIID: 1098624
• Length: 157
• Species: Mus musculus
• Alignment Length: 192
• Identity: 55/192 - (28%)
• Similarity: 82/192 - (42%)
• Gaps: 46/192 - (23%)

  Fly    14 QYRKVMKPMLERKRRARINKCLDELKDLMVATLESEGEHVTRLEKADILELTVTHLQKMKQQRQH 78
            :.||.:||:||::||||||:.|.:||.|::..|.:|....::||||||||:||..||:.......
Mouse    12 ELRKNLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRSSKLEKADILEMTVRFLQEQPATLYS 76

  Fly    79 KRASGDESLTPAEGFRSGYIHAVNEVSRSLSQLPGMNVSLGTQLMTHLGQRLNQIQPAEKEVLPV 143
            ..|.|     |...:..||...:..::|.|.....:..::..:|:.||.||..........:.|.
Mouse    77 SAAPG-----PLNSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSDDSPSLTLPPA 136

  Fly   144 TAPLSVHIANRDAYSVPISPISSYAGSPNSNTSSTSHSLLTTIDVTKMEDDSEDEENVWRPW 205
            .||         |.|.|:.|       |.|:                         .:||||
Mouse   137 PAP---------APSPPVPP-------PGSS-------------------------GLWRPW 157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mgamma-HLH	NP_524504.2	HLH	15..77	CDD:238036	30/61 (49%)
		ORANGE	91..135	CDD:128787	9/43 (21%)
Hes2	NP_001288734.1	bHLH_SF	10..73	CDD:381792	30/60 (50%)
		ORANGE	85..123	CDD:128787	8/37 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..157		11/73 (15%)
		WRPW motif	154..157		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830890
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	74	1.000	Inparanoid score	I5264
Isobase	1	0.950	-	0	Normalized mean entropy	S5317
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.840