Protein Alignment E(spl)mgamma-HLH and hes5.3

DIOPT Version :10

• Sequence 1: NP_524504.2
• Gene: E(spl)mgamma-HLH / 43151
• FlyBaseID: FBgn0002735
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: XP_002933894.1
• Gene: hes5.3 / 100101782
• XenbaseID: XB-GENE-480450
• Length: 160
• Species: Xenopus tropicalis
• Alignment Length: 198
• Identity: 53/198 - (26%)
• Similarity: 79/198 - (39%)
• Gaps: 62/198 - (31%)

  Fly    12 TYQYRKVMKPMLERKRRARINKCLDELKDLMVATLESEGEHV---TRLEKADILELTVTHL-QKM 72
            |.|..|:.|||:|:.||.|||..:::|::|    ||.|.:.:   ::.||||||||.|..| |::
 Frog    21 TKQKNKIRKPMVEKMRRDRINSSINQLQNL----LEKEFQLLQPDSKPEKADILELAVKFLKQQI 81

  Fly    73 KQQRQHKRASGDESLTPAEGFRSGYIHAVNEVSRSLSQLPGMNVSLGTQLMTHLGQRLNQIQPAE 137
            ..|.::.|..       .:.|..||.:.::|....||                       ....|
 Frog    82 CSQSKNNRKD-------YQDFSQGYSNCLHETFAFLS-----------------------FHRTE 116

  Fly   138 KEVLPVTAPLSVHIANRDAYSVPISPISSYAGSPNSNTSSTSHSLLTTIDVTKMEDDSEDEENVW 202
            :|   :...|..|....|:....||..||:...|....|            ||:         :|
 Frog   117 EE---MQLKLMNHFQCLDSQPRGISVSSSHQKGPGPVAS------------TKI---------LW 157

  Fly   203 RPW 205
            |||
 Frog   158 RPW 160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mgamma-HLH	NP_524504.2	bHLH-O_ESMB_like	9..77	CDD:381584	29/68 (43%)
		ORANGE	91..135	CDD:128787	6/43 (14%)
hes5.3	XP_002933894.1	bHLH-O_HES5	26..84	CDD:381467	26/61 (43%)
		Hairy_orange	93..135	CDD:470640	11/67 (16%)