Protein Alignment E(spl)mdelta-HLH and hes6

DIOPT Version :9

• Sequence 1: NP_524503.2
• Gene: E(spl)mdelta-HLH / 43150
• FlyBaseID: FBgn0002734
• Length: 173
• Species: Drosophila melanogaster
• Sequence 2: NP_919381.2
• Gene: hes6 / 373116
• ZFINID: ZDB-GENE-030828-5
• Length: 226
• Species: Danio rerio
• Alignment Length: 220
• Identity: 59/220 - (26%)
• Similarity: 86/220 - (39%)
• Gaps: 75/220 - (34%)

  Fly    16 RKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKADILELTVNYLKAQQQQRVANP 80
            ||..|||:|:|||||:|..|.||:.|:.|. |||    .|:|.|::||:||..:::..|.:
Zfish    20 RKTRKPLVEKKRRARINESLQELRLLLADP-DAQ----VKMENAEVLEMTVKRVESILQNK---- 75

  Fly    81 QSPPPDQVNL---DKFRAGYTQAAYEVSHIFSTVPGLDLKFGTHLMKQLGHQLKDM--KQEEEII 140
             :...|.||.   ::|.|||.|..:||....|:.||:|......|   |.|.|:.|  ..||...
Zfish    76 -AKEADSVNREANERFAAGYIQCMHEVHTFVSSCPGIDATIAADL---LNHLLECMPLNDEERFQ 136

  Fly   141 DMAEEPV--------------------------NLADQKRSKSPR------------EEDIHH-- 165
            |:..:.:                          |......|.:|.            :.|..|
Zfish   137 DILSDLISDSNNSGTWPGEAAYATLSPGGTSVANGGSSALSPAPSTTSSDDICSDLDDTDTEHSR 201

  Fly   166 -----------------GEEVWRPW 173
                             .:.:||||
Zfish   202 ISVDAGDQAPVVPTLYTNKSIWRPW 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mdelta-HLH	NP_524503.2	bHLH-O_ESMB_like	9..77	CDD:381584	28/60 (47%)
		ORANGE	91..135	CDD:128787	16/45 (36%)
hes6	NP_919381.2	HLH	18..75	CDD:238036	28/59 (47%)
		Hairy_orange	90..128	CDD:284859	15/40 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573606
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I5073
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.750