Protein Alignment E(spl)mdelta-HLH and her8a

DIOPT Version :9

• Sequence 1: NP_524503.2
• Gene: E(spl)mdelta-HLH / 43150
• FlyBaseID: FBgn0002734
• Length: 173
• Species: Drosophila melanogaster
• Sequence 2: NP_955918.3
• Gene: her8a / 323656
• ZFINID: ZDB-GENE-030131-2376
• Length: 221
• Species: Danio rerio
• Alignment Length: 215
• Identity: 58/215 - (26%)
• Similarity: 90/215 - (41%)
• Gaps: 52/215 - (24%)

  Fly     6 QRFMTKTQHYRKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKADILELTVNYLK 70
            :.|..|.:  ||:.|||:|:|||.|:|..|::||.::|   ||.....|||||||:||:||.:::
Zfish    12 KNFNAKEE--RKLRKPLIEKKRRERINSSLEQLKGIMV---DAYNLDQSKLEKADVLEITVQHME 71

  Fly    71 -AQQQQRVANPQSPPPDQVNLDKFRAGYTQAAYEVSHIFSTVPGLDLKFG----THLMKQLGHQL 130
             .|:........||.....:..::.:||.|..:||.::..:.||:|...|    .||:|.|.|..
Zfish    72 NLQRGHGQGGSNSPGTGFESRQRYSSGYIQCMHEVHNLLLSCPGMDKTLGARLLNHLLKSLPHIS 136

  Fly   131 KDMKQEEEI-------IDMAEEPVNLADQKR------SKSPREEDIHH----------------- 165
            .:.......       :...:.|:||....:      |.||.....|.
Zfish   137 TEPSGTSSAGTSSPLPLSPTQSPINLPSSLQPHALLLSPSPPSSPTHSLVRPREQSSPPSSPSPQ 201

  Fly   166 ------------GEEVWRPW 173
                        ...:||||
Zfish   202 SPASLPPFFPGVDPSMWRPW 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mdelta-HLH	NP_524503.2	bHLH-O_ESMB_like	9..77	CDD:381584	30/68 (44%)
		ORANGE	91..135	CDD:128787	14/47 (30%)
her8a	NP_955918.3	HLH	17..75	CDD:238036	29/62 (47%)
		Hairy_orange	95..133	CDD:284859	12/37 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573653
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I5073
OMA	1	1.010	-	-		QHG47782
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.860