DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment E(spl)mdelta-HLH and her9

DIOPT Version :9

Sequence 1:	NP_524503.2	Gene:	E(spl)mdelta-HLH / 43150	FlyBaseID:	FBgn0002734	Length:	173	Species:	Drosophila melanogaster
Sequence 2:	NP_571948.1	Gene:	her9 / 140613	ZFINID:	ZDB-GENE-011213-1	Length:	291	Species:	Danio rerio

Alignment Length:	162	Identity:	53/162 - (32%)
Similarity:	81/162 - (50%)	Gaps:	18/162 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 YRKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKADILELTVNYLKAQQQQRVAN 79
            :||.:||::|::||||:|..|.:||.||:|.:.....:.||||||||||:||.:|:  ..|||..
Zfish    34 HRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMTVKHLR--NLQRVQM 96

  Fly    80 PQSPPPDQVNLDKFRAGYTQAAYEVSHIFSTVPGLDLKFGTHLMKQLG----------------H 128
            ..:...|...|.|:|||:.:...||:...||..|::.:..:.|:..|.                .
Zfish    97 SAALSADTNVLSKYRAGFNECMNEVTRFLSTCEGVNTEVRSRLLNHLSGCMGQMMAMNYPQPAPA 161

  Fly   129 QLKDMKQEEEIIDMAEEPVNLADQKRSKSPRE 160
            |...:.|...:...:..|:|.|......||.|
Zfish   162 QQAHLAQPLHVQLPSTLPINGASMGSKLSPSE 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mdelta-HLH	NP_524503.2	bHLH-O_ESMB_like	9..77	CDD:381584	30/61 (49%)
E(spl)mdelta-HLH	NP_524503.2	ORANGE	91..135	CDD:128787	12/59 (20%)
her9	NP_571948.1	HLH	32..93	CDD:238036	29/60 (48%)
her9	NP_571948.1	Hairy_orange	110..147	CDD:284859	10/36 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573824
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840