DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment E(spl)mdelta-HLH and hes5.5

DIOPT Version :9

Sequence 1:	NP_524503.2	Gene:	E(spl)mdelta-HLH / 43150	FlyBaseID:	FBgn0002734	Length:	173	Species:	Drosophila melanogaster
Sequence 2:	NP_001165751.1	Gene:	hes5.5 / 100337645	XenbaseID:	XB-GENE-6492485	Length:	158	Species:	Xenopus tropicalis

Alignment Length:	169	Identity:	47/169 - (27%)
Similarity:	74/169 - (43%)	Gaps:	34/169 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KTQHYRKVTKPLLERKRRARMNLYLDELKDLIVDTMDAQGEQVSKLEKADILELTVNYLKAQQQQ 75
            |.|..||:.||::|:.||.|:|..:::|:.|:....|:. ...||.|||||||:.|:::  |||.
Frog    17 KAQGIRKMRKPVVEKMRRDRINSSIEQLRMLLEKEFDSH-HLPSKPEKADILEVAVSFM--QQQM 78

  Fly    76 RVANPQSPPPDQVNLDKFRAGYTQAAYEVSHIFSTVPGLDLKFGTHLMKQLGHQLKDMKQEEEII 140
            .....||....|:.      ||::...:..|..|.                   .|..:...::|
Frog    79 ATKCKQSSSAPQME------GYSKCLQDSLHFLSL-------------------QKHAELHRKVI 118

  Fly   141 DMAEEPVNLADQK-RSKSPREEDIHHG-----EEVWRPW 173
            ....|..:|:... ||.||..:....|     :.:||||
Frog   119 QNFHENHSLSQGLCRSVSPYYQTPTIGTAPPAKLLWRPW 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mdelta-HLH	NP_524503.2	bHLH-O_ESMB_like	9..77	CDD:381584	27/65 (42%)
E(spl)mdelta-HLH	NP_524503.2	ORANGE	91..135	CDD:128787	5/43 (12%)
hes5.5	NP_001165751.1	bHLH-O_HES5	23..77	CDD:381467	22/56 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1378299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010