| Sequence 1: | NP_733132.2 | Gene: | Nf1 / 43149 | FlyBaseID: | FBgn0015269 | Length: | 2802 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_031394.2 | Gene: | RASA3 / 22821 | HGNCID: | 20331 | Length: | 834 | Species: | Homo sapiens |
| Alignment Length: | 816 | Identity: | 167/816 - (20%) |
|---|---|---|---|
| Similarity: | 294/816 - (36%) | Gaps: | 216/816 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 926 EKIGLNIQKNVKELVGEEMSTQLYP-----------ILFDQVRA----IVEK----FF--DQQGQ 969
Fly 970 VNVNVTDINTQFIEHTIYIMKSILDPKA------NKDPNNDQPSPSEHLGVTS-IEGMMLGIVRY 1027
Fly 1028 VRHLDMTVYAI---------RIKTKL--CQLVEVMMKRRDDLA-------FRQEMKFRNKLVEYL 1074
Fly 1075 TDWVMGTSHQIAPPSSADAAILTNT----SLIFRDLDQACMEAVAALLRGLPLQPEESDRGDL-M 1134
Fly 1135 DAKSALFLKYFTLFMNLLNDCIDSSEAEKEMNNTPLLPPRPR----MAAGKLTALRNATILAMSN 1195
Fly 1196 LLGANIDSGLMHSIDLGYNP--DLQTRAAFMEVLTQILQQGTEFDTLAETVLADRFEQLVQLVTM 1258
Fly 1259 ISDKGELPIAMALANVV--TTSQMDELARVLVTLFDAKHLLSPLLWNMFYREVEVSDCMQTLFRG 1321
Fly 1322 NSLGSKIMAFCFKIYGASYLQMLLEPLIRPLLDEEEETC-----FEVDPARLDPTEDIEQHRNNL 1381
Fly 1382 IALTQKVFDAIINSSDRFPPQLRSMCHCLYQVLSKRFPNLLQNNIGAVGTVIFLRFINPAIVSPQ 1446
Fly 1447 ELGIVDKQVHSSAKRGLMLMSKILQNI-----ANHVEFSKEQHMLCFNDFLRD--HFEAGRRFFI 1504
Fly 1505 QIAS----DCETVDQTSHSMSFISDANVLALHRLLWTHQEKIGDYLSSSRDHKAVGRRPFDKMAT 1565
Fly 1566 LLAYLGPPEHKPVDSHMMFSSYARWSSIDMSSTNFEEIMVKHQMHEKEEFKTLKSM--------N 1622
Fly 1623 IFYQAGTSKSGYPVFYYIARRYKIGETNGD-LLIYH 1657 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Nf1 | NP_733132.2 | RasGAP_Neurofibromin | 1242..1575 | CDD:213332 | 87/350 (25%) |
| CRAL_TRIO_2 | 1633..1767 | CDD:404584 | 6/26 (23%) | ||
| PH_NF1 | 1759..1868 | CDD:270123 | |||
| MOR2-PAG1_mid | <1931..>2109 | CDD:372971 | |||
| RASA3 | NP_031394.2 | C2A_RasA2_RasA3 | 13..133 | CDD:176046 | 25/127 (20%) |
| C2B_RasA3 | 146..288 | CDD:175977 | 27/168 (16%) | ||
| RasGAP_RASA3 | 297..565 | CDD:213336 | 82/326 (25%) | ||
| PH_GAP1_mammal-like | 562..686 | CDD:241522 | 29/161 (18%) | ||
| BTK | 679..714 | CDD:128417 | 4/9 (44%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R472 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.940 | |||||