Protein Alignment boss and gprc5cl2

DIOPT Version :10

• Sequence 1: NP_542440.1
• Gene: boss / 43146
• FlyBaseID: FBgn0000206
• Length: 896
• Species: Drosophila melanogaster
• Sequence 2: XP_012822967.1
• Gene: gprc5cl2 / 496865
• XenbaseID: XB-GENE-923223
• Length: 407
• Species: Xenopus tropicalis
• Alignment Length: 454
• Identity: 93/454 - (20%)
• Similarity: 171/454 - (37%)
• Gaps: 131/454 - (28%)

  Fly   464 REIASQNFV-------------TNVTTYYHYNRDNHTSLELKTKFGQVFNCQYSAGDNRRYPFLF 515
            :::||::|:             .|:||         .|:||:........|..
 Frog     8 KKMASKHFLLILYMLGPLGAASLNLTT---------PSVELQNLSAVPMGCSQ------------ 51

  Fly   516 DGESVMF--------WRIKMDTWVATGLTAAILGLIATLAILVFIVVRISLGDVFEGNPTTSILL 572
            |.:.:.:        |.|.::.....|:..|::     ||::...:....:.|..:|:      |
 Frog    52 DVQPIFYALCDLNAAWGIILEALAGLGIVCALV-----LAVIFLALAPSVIRDERKGS------L 105

  Fly   573 LLSLILVFCSFVPYSIEYVGEQRNSHVTFEDAQTLNTLCAVRVFIMTLVYCFVFSLLLCRAV--- 634
            .::.:.:|..|..:|:.:      :.:...:|    .:|.||.|:..:::...|:.|:..:|
 Frog   106 AINFMFLFGVFGLFSLVF------AFIIAPNA----AVCEVRRFLFGVLFALCFACLVAHSVRLN 160

  Fly   635 --MLASIGSEGGFLSHVNGYIQAVICAFSVVAQVGMSVQLLV-VMHVASETVS----CE------ 686
              :|.:.|..||.:     ::.| |..|.|.|.:.....|:. |.|..|.|||    |:
 Frog   161 YLVLHNRGPGGGLI-----FLLA-IGLFLVEAVINAEWLLITNVRHNLSSTVSVGHPCQIDNQDF 219

  Fly   687 ---NIYYGRWLWGLLAYDFALLCCVGALIPSIYRSQRNYREGILIVIGSVLIMVIWVAWIALSLF 748
               .:|....:...|.....:||  |..:|.       .|.|..||:.::|.:.|||.||.:.::
 Frog   220 VTALVYVMFLILASLIVPCPVLC--GHYLPW-------KRHGRYIVVTALLSLSIWVTWIVMYVY 275

  Fly   749 GDE-------WRDAAIPLGLQASGWAVLVGILIPRTFLIVR---GIERSDI-----AQALPS--- 795
            |:|       |.|..:.:.|.::||..:|...||....:.|   |.|...:     .:..||
 Frog   276 GNEKLGHQNTWDDPVLAIALVSNGWVFIVCYFIPEVVEMTRTGYGYETDTLNMIKRFEECPSSII 340

  Fly   796 LTSLAFAQNNQYSSEQSVY-----ECVNPAMRHC-----------SQDEVNHQSPSEIPTLPLR 843
            :.:.||:..|...::|...     :.|:|...:|           ..:.|||.....|.|.|.|
 Frog   341 VENRAFSMENLEMTDQRETIKIQDKPVSPYSNYCGLYPTLPLYPTEVETVNHVPLPRISTEPWR 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
boss	NP_542440.1	7tmC_Boss	529..782	CDD:320170	61/278 (22%)
		TM helix 1	529..554	CDD:320170	4/24 (17%)
		TM helix 2	566..587	CDD:320170	3/20 (15%)
		TM helix 3	612..636	CDD:320170	6/28 (21%)
		TM helix 4	656..672	CDD:320170	4/15 (27%)
		TM helix 5	690..716	CDD:320170	5/25 (20%)
		TM helix 6	724..747	CDD:320170	9/22 (41%)
		TM helix 7	751..776	CDD:320170	8/31 (26%)
gprc5cl2	XP_012822967.1	7tmC_RAIG3_GPRC5C	66..316	CDD:320404	63/285 (22%)
		TM helix 1	66..91	CDD:320404	6/29 (21%)
		TM helix 2	105..126	CDD:320404	4/26 (15%)
		TM helix 3	135..159	CDD:320404	6/23 (26%)
		TM helix 4	176..192	CDD:320404	5/16 (31%)
		TM helix 5	215..241	CDD:320404	2/25 (8%)
		TM helix 6	251..274	CDD:320404	9/22 (41%)
		TM helix 7	285..310	CDD:320404	7/24 (29%)