Protein Alignment boss and gprc5b

DIOPT Version :10

• Sequence 1: NP_542440.1
• Gene: boss / 43146
• FlyBaseID: FBgn0000206
• Length: 896
• Species: Drosophila melanogaster
• Sequence 2: XP_004918020.1
• Gene: gprc5b / 100491763
• XenbaseID: XB-GENE-981355
• Length: 390
• Species: Xenopus tropicalis
• Alignment Length: 400
• Identity: 86/400 - (21%)
• Similarity: 156/400 - (39%)
• Gaps: 102/400 - (25%)

  Fly   510 RYPFLFDGESVMFWRIKMDTWVATGLTAAILGLIATLAILVFIVVRISLGDVFEGNPTTSI--LL 572
            ||.:|.|.:::  |.|.::       ..|..|::.||.:::.::||:......|......|  |.
 Frog    36 RYVYLCDLDAI--WGIVVE-------AVAGAGVLTTLLLMLILLVRLPFITEKEKKSPLGIHFLF 91

  Fly   573 LLSLILVFCSFVPYSIEYVGEQRNSHVTFEDAQTLNTLCAVRVFIMTLVYCFVFSLLLCRAVMLA 637
            ||..:.:|.....:.|:            ||    ..:|..|.|:..:::...||.||.:...:.
 Frog    92 LLGTLGLFGLAFAFIIQ------------ED----EAICCTRRFLWGVLFALCFSCLLAQGWRIR 140

  Fly   638 SIGSEGGFLS--HVNGYIQAVICAFSVVAQVGMSVQLLVVMHVASETVSCEN---------IYYG 691
            .:...|...|  |:.|   .|||.  ::.||.::|:.:::..|....::|..         ||..
 Frog   141 RLVRHGKSPSGWHMVG---MVICL--MLVQVIIAVEWIILTVVRDRKLACSYEPMDFVMVLIYVM 200

  Fly   692 RWLWGLLAYDFALLCCVGALIPSIYRSQRNYREGILIVIGSVLIMVIWVAWIALSLFG------- 749
            ..:...|...|..||         .:.|:..:.||.::|.::..::|||||:.:.|:|
 Frog   201 VLMVATLGLSFFTLC---------GKFQKWKKNGICLIITTLFSVLIWVAWMTMYLYGNNELKRS 256

  Fly   750 DEWRDAAIPLGLQASGWAVLV--GILIPRTFLIVRGIERS----DIAQ------------ALPSL 796
            |:|.|..:.:.|.:|||..|:  .|:.....::....|.:    |.:|            .||.
 Frog   257 DKWNDPTLAIALISSGWVFLIFHAIIEVHCTILPAPQENTTNYFDTSQPRMRETPFEEDIQLPR- 320

  Fly   797 TSLAFAQNNQYSSEQSVYECVNPAMRHCSQDEVNHQSPSEIPTLPLR-------------GGGPR 848
               ::.:|..:|.::.     |.|||   .....:.|....|:.|.|             .||..
 Frog   321 ---SYMENKAFSMDEH-----NAAMR---AGGFRNGSLGSRPSAPFRSNVYQPTEMAVVLNGGTD 374

  Fly   849 RQQFFANLRQ 858
            ..||..|.::
 Frog   375 ILQFILNQKE 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
boss	NP_542440.1	7tmC_Boss	529..782	CDD:320170	60/274 (22%)
		TM helix 1	529..554	CDD:320170	4/24 (17%)
		TM helix 2	566..587	CDD:320170	5/22 (23%)
		TM helix 3	612..636	CDD:320170	6/23 (26%)
		TM helix 4	656..672	CDD:320170	6/15 (40%)
		TM helix 5	690..716	CDD:320170	4/25 (16%)
		TM helix 6	724..747	CDD:320170	8/22 (36%)
		TM helix 7	751..776	CDD:320170	8/26 (31%)
gprc5b	XP_004918020.1	7tmC_RAIG2_GPRC5B	46..289	CDD:320405	62/281 (22%)
		TM helix 1	46..71	CDD:320405	6/33 (18%)
		TM helix 2	85..106	CDD:320405	5/20 (25%)
		TM helix 3	115..139	CDD:320405	6/23 (26%)
		TM helix 4	156..172	CDD:320405	7/20 (35%)
		TM helix 5	188..211	CDD:320405	3/22 (14%)
		TM helix 6	224..247	CDD:320405	8/22 (36%)
		TM helix 7	258..283	CDD:320405	8/24 (33%)