Protein Alignment CG42235 and SLC5A6

DIOPT Version :9

• Sequence 1: NP_651446.2
• Gene: CG42235 / 43136
• FlyBaseID: FBgn0250757
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_066918.2
• Gene: SLC5A6 / 8884
• HGNCID: 11041
• Length: 635
• Species: Homo sapiens
• Alignment Length: 642
• Identity: 208/642 - (32%)
• Similarity: 312/642 - (48%)
• Gaps: 86/642 - (13%)

  Fly    38 ISSTVSTSSTTGATSTISTSSSTPTTSTTFAYTPTPTPTQSASPSLEDGEEKLSVKDLSQALQHF 102
            :|..||||:....||..|...||                                         |
Human     1 MSVGVSTSAPLSPTSGTSVGMST-----------------------------------------F 24

  Fly   103 GIVDYLVFIAMLAVCAVIGFYFGFIEKKQKKQKLAGKDGGGAAGVEERRGSEALDYLVGGRQMKV 167
            .|:||:||:.:|.:...||.|...             .|.|...|.|        .|:..|:|..
Human    25 SIMDYVVFVLLLVLSLAIGLYHAC-------------RGWGRHTVGE--------LLMADRKMGC 68

  Fly   168 FPVALSLVASFVSGISLLGTSTEIYVYGTQYAFILVTLAISGAISWYIFLPVFCNLQLTSTYEYF 232
            .||||||:|:|.|.:::||..:|||.:||||.|:.....:...|..:||:|||..|.|||.|||.
Human    69 LPVALSLLATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYL 133

  Fly   233 ERRFDRRVRIFGSCLFVVMNILWQPICIYVPALTLNQVSGISVSKIVPVTSFICILYTSVGGIKG 297
            |.||::.||:.|:..|:...:::..:.:|.|:|.||.|:|..:...|.....:|.:||::||:|.
Human   134 ELRFNKTVRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKA 198

  Fly   298 VVWTDVIQGTVMIGSMLIVIIKGTLDLGGLSVVLDHNRQYDRLVGPDMTFDPTARMGVFALFVGG 362
            |:||||.|..||....|.|||.|:..:|||..|.....|:.|:.|.::..||..|...:.|..||
Human   199 VIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTFWTLAFGG 263

  Fly   363 ALFKLQANGINQAIVQRYLTLPNNKDVKKALVLSLIG-FMFVML-MCV--YIGLLAFAEFYHCDP 423
            ....|...|:|||.|||||    :...:||.|||... |.|..: :||  .|||:.|| :|...|
Human   264 VFMMLSLYGVNQAQVQRYL----SSRTEKAAVLSCYAVFPFQQVSLCVGCLIGLVMFA-YYQEYP 323

  Fly   424 ITTGLAR-AKDQVIPLYVVKNVGHIPGLVGLFVAGVFSAALSSLSTALNSLSGVILTDFVEPFRK 487
            ::...|: |.||.:..:|:..:..:|||.|||:|.:||.:||::|:|.|||:.|.:.|.:.|:..
Human   324 MSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFP 388

  Fly   488 KPLTERQTAYLLRGVVISFGLISMASVPIVQRLGLVMQLSSTVAAITCGPLLGAFSVGMLLPFVK 552
            : .:|.:...|.||:...:||:.:....|..::|.|:|.:.::..:..|||||.|.:||..|...
Human   389 E-FSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCAN 452

  Fly   553 TESLLTGISCASSFTAYIVVRAQIAIFTGSLTFPAKPVSIQDCDYTFDLPANWNATTTAT----P 613
            ....:.|: .|....|:.:....|....|| :.|..|.:    ..:|.||.|....|..|    .
Human   453 PPGAVVGL-LAGLVMAFWIGIGSIVTSMGS-SMPPSPSN----GSSFSLPTNLTVATVTTLMPLT 511

  Fly   614 TESTSHGI---HEISFLWYTAVGSVGTVLGSLLATLYFGRQDPRVVDKELISPVLRK 667
            |.|...|:   :.:|:|||:|..|...::..|:.:|..||...|.::...|.|||.|
Human   512 TFSKPTGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSLNPATIYPVLPK 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	187/552 (34%)
SLC5A6	NP_066918.2	SLC5sbd_SMVT	24..550	CDD:271394	190/558 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.820