Protein Alignment CG42235 and DUR3

DIOPT Version :9

• Sequence 1: NP_651446.2
• Gene: CG42235 / 43136
• FlyBaseID: FBgn0250757
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_011847.1
• Gene: DUR3 / 856370
• SGDID: S000001008
• Length: 735
• Species: Saccharomyces cerevisiae
• Alignment Length: 662
• Identity: 152/662 - (22%)
• Similarity: 259/662 - (39%)
• Gaps: 142/662 - (21%)

  Fly   107 YLVFIAMLAVCAVIGFYFGFIEKKQKKQKLAGKDGGGAAGVEERRGSEALDYLVGGRQMKVFPVA 171
            |.:.:.:.||.|.:.....::.|:.:|:.:.                 |.::...||.:|...||
Yeast    14 YAIVLGLGAVFAGMMVLTTYLLKRYQKEIIT-----------------AEEFTTAGRSVKTGLVA 61

  Fly   172 LSLVASFVSGISLLGTSTEI--------YVYGTQYAFILVTLAISGAISWYIFLPVFCNLQLTST 228
            .::|:|::...:||.:||:.        |.|.....|.::..||         |.:.......:.
Yeast    62 AAVVSSWIWCSTLLTSSTKEYADGIFGGYAYAAGACFQIIAFAI---------LAIKTKQMAPNA 117

  Fly   229 YEYFERRFDRRVRIFGSC-LF--VVMNILWQPICIYVPALTLNQVSG---ISVSKIVPVTSFICI 287
            :.|.|....|..:|...| ||  :..|||...:.:...:...:.::|   |:...::||.   .:
Yeast   118 HTYLELVRTRYGKIGHGCYLFYAIATNILVTSMLLTSGSAVFSDLTGMNTIASCFLLPVG---VV 179

  Fly   288 LYTSVGGIKGVVWTDVIQGTVMIGSMLIVIIK--GTLD-LGGLSVVLDHNRQYDR-------LVG 342
            :||..||||....||.:...|:|..:|:...|  .|.| ||....|.|..|:..:       ..|
Yeast   180 VYTLFGGIKATFLTDYMHTCVIIIIVLVFAFKVYATSDVLGSPGKVYDLVREAAKRHPVDGNYQG 244

  Fly   343 PDMTFDPTARMGVFALFVG-----GALFKLQANGI-NQAIVQRYLTLPNNKDVKKALVLSLIGFM 401
            ..||.  |::.....|.:.     |.:|  ..||. |:||     :......:|...:..|..|.
Yeast   245 EYMTM--TSKSAGILLIINLIGNFGTVF--LDNGYWNKAI-----SASPAASLKAYAIGGLAWFA 300

  Fly   402 FVMLMCVYIGLLAFA-----EF-YHCDPITTGLARAKDQVIPLYVVKNVGHIPGLVGLFVAGVFS 460
            ...|:.:.:||...|     .| .:.||:|:..|.: ..|:|...:..:|....:..|.:  :|.
Yeast   301 VPSLISLTMGLACLAVETSPNFPTYPDPLTSFQANS-GLVLPAAAIAIMGKGGAVASLLM--IFM 362

  Fly   461 AALSSLSTALNSLSGV----ILTDFVEP--FRKKPLTERQTAYLLRGVV------------ISFG 507
            |..|::|..|.::|.|    |..::::|  ..||.:.....|.:..|:.            ||.|
Yeast   363 AVTSAMSAELIAVSSVFTYDIYREYIDPRASGKKLIYTSHVACIFFGLAMSGFSVGLYYGGISMG 427

  Fly   508 --------LISMASVPIVQRLGLVMQLSSTVAAITCGPLLGAFSVGMLLPFVKTESLLTGISCAS 564
                    :||.|.:|:|  |.|..:..:.|||:. .|:||. .:.::...|.|:||...::..:
Yeast   428 YIYEMMGIIISSAVLPVV--LTLCSKDMNLVAAVV-SPILGT-GLAIMSWLVCTKSLYKELTVDT 488

  Fly   565 SFTAY------IVVRAQIAIFTGSLTFPAKPVSIQDCDYTFDLPANWNATTTATPTESTSHGIH- 622
            :|..|      :|.....|||...||:..||       ..||    |......|..:.|:..:.
Yeast   489 TFMDYPMLTGNLVALLSPAIFIPILTYVFKP-------QNFD----WEKMKDITRVDETAELVQA 542

  Fly   623 EISFLWYTAVGS---VGTVLGSLLATLYFGRQDPRVVDKELISPVLRKFWYGKYESVASEEKNNF 684
            :.....|.|..:   ......||::.  ..:.|.||.:::||.|.|     |...|       |.
Yeast   543 DPDIQLYDAEANDKEQEEETNSLVSD--SEKNDVRVNNEKLIEPNL-----GVVIS-------NA 593

  Fly   685 NLHESETQLKLE 696
            ...|.:|||:.|
Yeast   594 IFQEDDTQLQNE 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	137/610 (22%)
DUR3	NP_011847.1	SLC5sbd_DUR3	14..517	CDD:271370	126/547 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I2754
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I1755
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
TreeFam	0	0.000	Not matched by this tool.
	5	4.860