Protein Alignment CG42235 and SLC5A4

DIOPT Version :9

• Sequence 1: NP_651446.2
• Gene: CG42235 / 43136
• FlyBaseID: FBgn0250757
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: XP_016884409.1
• Gene: SLC5A4 / 6527
• HGNCID: 11039
• Length: 689
• Species: Homo sapiens
• Alignment Length: 610
• Identity: 135/610 - (22%)
• Similarity: 247/610 - (40%)
• Gaps: 121/610 - (19%)

  Fly   144 AAGVEERRGSEALDYLVGGRQMKVFPVALSLVASFVSG---ISLLGTSTEIYVYGTQYAFILVTL 205
            :|.::..||:.. .:.:.||.|..:|:..||.||.:..   :.|.||.....|....:.:   |.
Human    75 SAMLKTNRGTIG-GFFLAGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEW---TS 135

  Fly   206 AISGAISWYIFLPVFCNLQLTSTYEYFERRFDRRVRIFGSCLFVVMNILWQPIC--------IYV 262
            ::...|..:||:|::....:.:..||.::||.      |..|.|.::||...||        |:.
Human   136 SVMLLILGWIFVPIYIKSGVMTMPEYLKKRFG------GERLQVYLSILSLFICVVLLISADIFA 194

  Fly   263 PALTLNQVSGISVSKIVPVTSFICILYTSVGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLDLGGL 327
            .|:.:....|:.:...:.:...:..:||:.||:..|::||.:|..:|:....|::.....::||.
Human   195 GAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGY 259

  Fly   328 SVVLDH--NRQYDRLVGPDMTFDP---TARMGVFALF----VG-----GALFKLQANGI-----N 373
            ....:.  |.....:.|.::|...   |.|...|.:|    .|     |.:|.:....:     |
Human   260 ESFTEKYVNATPSVVEGDNLTISASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYWCTN 324

  Fly   374 QAIVQRYLTLPNNKDVKKALV----LSLIGFMFVMLMCVYIGLLAFAEFYHCDPITTGLARAKDQ 434
            |.||||.|...:...||.|.:    |.|:. ||:|:|...|..:.:.:...|
Human   325 QVIVQRCLCGKDMSHVKAACIMCAYLKLLP-MFLMVMPGMISRILYTDMVAC------------- 375

  Fly   435 VIPLYVVKNVG----------------HIP-GLVGLFVAGVFSAALSSLSTALNSLSGVILTDFV 482
            |:|...||:.|                .:| ||.||.::.:.::.:|||::..||.|.:...|..
Human   376 VVPSECVKHCGVDVGCTNYAYPTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLY 440

  Fly   483 EPFRKKPLTERQTAYLLRGVVISFGLISMASVPIVQ--RLGLVMQLSSTVAAITCGPLLGAFSVG 545
            ...||: .:|::.....|..|:...::|:..||:||  :.|.::..:.::::....|:...|.:.
Human   441 TKMRKQ-ASEKELLIAGRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLA 504

  Fly   546 MLLPFVKTESLLTGISCASSFTAYIVVRAQIAIFTGSLTFPAK-PVSIQDCDYTFDLPANWNATT 609
            :....|..:....|:....:. ..|.:..:.|..|||...|:. |..|  |
Human   505 IFCKRVNEQGAFWGLMVGLAM-GLIRMITEFAYGTGSCLAPSNCPKII--C-------------- 552

  Fly   610 TATPTESTSHGIHEISFLWYTAVGSVGTVLGSLLATLYFGRQDPRVVDKEL--ISPVLRKFWYGK 672
                      |:|.:.|       |:....||:|.||........:.|..|  :..|||.....:
Human   553 ----------GVHYLYF-------SIVLFFGSMLVTLGISLLTKPIPDVHLYRLCWVLRNSTEER 600

  Fly   673 YESVASEEKNNFNLHESETQLKLEQ 697
            .: :.:|||:     :.||...:|:
Human   601 ID-IDAEEKS-----QEETDDGVEE 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	122/555 (22%)
SLC5A4	XP_016884409.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146498
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740