Protein Alignment CG42235 and slc5a9

DIOPT Version :9

• Sequence 1: NP_651446.2
• Gene: CG42235 / 43136
• FlyBaseID: FBgn0250757
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001107077.1
• Gene: slc5a9 / 564815
• ZFINID: ZDB-GENE-080513-3
• Length: 657
• Species: Danio rerio
• Alignment Length: 677
• Identity: 153/677 - (22%)
• Similarity: 274/677 - (40%)
• Gaps: 160/677 - (23%)

  Fly    72 TPTPTQSASPSLEDGEEKLSVKDLSQALQHFGIVDYLVFIAMLAVCAVIGFYFGFIEKKQKKQKL 136
            :|.|. :|:|..|:...|.:::....|:    :|.|.||:  |||
Zfish     4 SPEPV-TATPEPEEVPAKFTLEAADIAV----VVVYFVFV--LAV-------------------- 41

  Fly   137 AGKDGGGAAGVEERRGSEALDYLVGGRQMKVFPVALSLVASFV-SG--ISLLGTSTE--IYVYGT 196
                 |..:.:...||:.. .|.:.||.|..:|:..||::|.| ||  |.|.||...  :.|.|.
Zfish    42 -----GIWSSIRANRGTVG-GYFLAGRSMTWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGF 100

  Fly   197 QY--AFILVTLAISGAISWYIFLPVFCNLQLTSTYEYFERRF-DRRVRIFGSCLFVVMNILWQ-P 257
            ::  |::|:      |:.| ||:||:.:..:.:..||..:|| .:|:||:.|.|.:::.||.: .
Zfish   101 EWNAAWVLI------ALGW-IFVPVYISAGVVTMPEYLRKRFGGQRIRIYMSVLSLILYILTKIS 158

  Fly   258 ICIYVPALTLNQVSG----ISVSKIVPVTSFICILYTSVGGIKGVVWTDVIQGTVM-IGSMLIVI 317
            ..|:..||.:....|    :|...::.||:    |||..||:..|::||.:|..:| ||:.:::.
Zfish   159 TDIFSGALFIQVSLGWDLYLSTVILLAVTA----LYTIAGGLTAVIYTDALQTVIMVIGAFVLMF 219

  Fly   318 IK----GTLDLGGLSVVLDHNRQYDRLVGPDMTFDPTA----RMGVFALF----VG-----GALF 365
            |.    |..:  ||.|      ||:: ..|.:|...|.    |...|.:|    .|     |.:|
Zfish   220 IAFDKVGWYE--GLLV------QYEK-AAPALTVPNTTCHLPRSDAFHIFRDPVTGDIPWPGLIF 275

  Fly   366 KLQANG-----INQAIVQRYLTLPNNKDVKKALVLSLIGFM--FVMLMCVYIGLLAFAEF----- 418
            .|....     .:|.||||.|:..|....|...||.  |::  |.|...|..|:::.|.:
Zfish   276 GLTVLATWVWCTDQVIVQRSLSAKNLSHAKAGSVLG--GYLKVFPMFFVVMPGMISRALYPDEVA 338

  Fly   419 ----YHCDPITTGLARAKDQVIPLYVVKNVGHIP-GLVGLFVAGVFSAALSSLSTALNSLSGVIL 478
                ..|..|........:...|..||:   .:| |:.||.:|.:.:|.:|||::..||.|.:..
Zfish   339 CVDPDECQKICGAKVGCSNIAYPKLVVE---LMPVGMRGLMIAVMMAALMSSLTSIFNSSSTLFT 400

  Fly   479 TDFVEPFRKKPLTERQTAYLLRGVVISFGLISMASVPIVQ--RLGLVMQLSSTVAAITCGPLLGA 541
            .|..:..|.: .:|::...:.|..::....:|:..:|::|  ..|.:......:.:....|:...
Zfish   401 MDIWQRIRPR-ASEKELMVVGRVFILLLVALSIVWIPVIQTANSGQLFDYIQAITSFLSPPITTV 464

  Fly   542 FSVGMLLPFVKTESLLTGISCASSFTAYIVVRAQIAIFTGSLTFPAKPVSIQDCDYTFDLPANWN 606
            |.:.:....|..:....|:              .:.:..|.:..      |.:..|
Zfish   465 FIMAIFWGRVNEQGAFWGL--------------MVGLVVGMVRM------IMEFVY--------- 500

  Fly   607 ATTTATPTESTSHGIHEISFLWYTAVGSVGTVLGSLLATLYFGRQDPRVVDKELISPVLRKFWYG 671
            .|.:...|:.....:.::.:|::..:....|||.....:|.    ...:.:|.|:    |..|:.
Zfish   501 GTPSCGETDLRPSLLKDVHYLYFALILLALTVLIITAVSLC----TAPIPEKHLV----RLTWWT 557

  Fly   672 KYESVASEEKNNFNLHESETQLKLEQP 698
            :              |..|.:::||.|
Zfish   558 R--------------HSKEERVELEDP 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	136/590 (23%)
slc5a9	NP_001107077.1	SLC5sbd_SGLT4	42..657	CDD:271380	139/607 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580046
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740