Protein Alignment CG42235 and slc5a11

DIOPT Version :9

• Sequence 1: NP_651446.2
• Gene: CG42235 / 43136
• FlyBaseID: FBgn0250757
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001007301.1
• Gene: slc5a11 / 492334
• ZFINID: ZDB-GENE-041114-9
• Length: 668
• Species: Danio rerio
• Alignment Length: 684
• Identity: 151/684 - (22%)
• Similarity: 279/684 - (40%)
• Gaps: 150/684 - (21%)

  Fly    64 STTFAYTPTPTPTQSASPSLEDGEEKLSVKDLSQALQHFGIVDYLVFIAMLAVCAVIGFYFGFIE 128
            :.|.|...:||||...:..    :..|:..|:        :|..:.|:.:|||    |.:
Zfish     2 AATEAPDASPTPTSDGTAQ----QTTLATTDI--------VVLVIYFLLVLAV----GLW----- 45

  Fly   129 KKQKKQKLAGKDGGGAAGVEERRGSEALDYLVGGRQMKVFPVALSLVASFV-SG--ISLLGTSTE 190
             ...|.|.:..||                |.:.|:.|..:||..||.||.| ||  |.|.|:...
Zfish    46 -SMWKTKRSTVDG----------------YFLAGKNMTWWPVGASLFASNVGSGHFIGLAGSGAA 93

  Fly   191 IYVYGTQYAF--ILVTLAISGAISWYIFLPVFCNLQLTSTYEYFERRF-DRRVRIFGSCLFVVMN 252
            ..:....|.:  :|:.|.:.     ::|||::...::|:..||.::|| .:|:::|...|::.:.
Zfish    94 AGIGAVAYEWNGMLMVLVMG-----WLFLPIYIASRVTTMPEYLKKRFGGKRIQLFLCVLYLFIY 153

  Fly   253 ILWQ-PICIYVPALTLNQVSGISVSKIVPVTSFICILYTSVGGIKGVVWTDVIQGTVMIGSMLIV 316
            |..: .:.:|..|:.:.|....::...|.:...|..|||..||:..|::||.:|..:|:...||:
Zfish   154 IFTKISVDMYAGAVFIQQALQWNIYLAVVLLLGITALYTIAGGLAAVIYTDAVQTIIMVIGALIL 218

  Fly   317 IIKGTLDLGGLSVVLDHNRQYDRLVGPDMTFDPTARMGV-----FALFVGGALFKLQANGI---- 372
            :.....::||...|||   :|.:.: |.:.. |....|:     |.:|.......|...|:
Zfish   219 MGFSFAEVGGFEAVLD---KYPQAI-PSIRV-PNTTCGIPRDDAFHIFRHPVTSDLPWPGVILGM 278

  Fly   373 ----------NQAIVQRYLTLPNNKDVK----KALVLSLIGFMFVMLMCVYIGLLAFAEFYHC-D 422
                      :|.||||.|...|....|    .|..:.::.| |:|::...|..:.:.:...| |
Zfish   279 SIPSMWYWCSDQVIVQRSLAAKNILHAKGGSLLAAYIKVLPF-FMMVIPGMISRILYPDEVGCGD 342

  Fly   423 PIT-----------TGLARAK--DQVIPLYVVKNVGHIPGLVGLFVAGVFSAALSSLSTALNSLS 474
            |..           :.:|.||  .:::|          .||.||.:|.:.:|.:|||::..||.|
Zfish   343 PEVCKEVCGNSVGCSDIAYAKLVMELLP----------AGLRGLMMAVMLAALMSSLTSIFNSSS 397

  Fly   475 GVILTDFVEPFRKKPLTERQTAYLLRGVVISFGLISMASVPIVQRLGLVMQLSSTVAAITCGPLL 539
            .:...|.....| ...:|.:...:.|..|:...::|:..:|:||
Zfish   398 TIFTMDLWRNIR-HTASEWELMIVGRVFVLVLVVVSVLWIPLVQ--------------------- 440

  Fly   540 GAFSVGMLLPFVKTESL-----LTGISCASSFTAYIVVRAQIAIFTGSLTFPAKPVSIQDCDYTF 599
             |...|.|..::::.|:     :|.|..|..|...   ..:...|.|.:...|...:....|:.:
Zfish   441 -ASQGGQLFIYIQSISMYLQPPITVIFVAGCFWKR---TNEKGAFWGLMVGMAVGCTRMILDFIY 501

  Fly   600 DLPANWNATTTATPTESTSHGIHEISFLWYTAVGSVGTVLGSLLATLYFGRQDPRVVDKELISPV 664
            ..|..:.:.|....       |..:.||:::.:.::.|::..:..:|...:..|     |.||
Zfish   502 PTPQCYESDTRPDI-------IKYVHFLYFSIILTILTLVVVVCVSLATEKPKP-----EQIS-- 552

  Fly   665 LRKFWYGKYESV-ASEEKNNFNLHESETQLKLEQ 697
             |..||.::::| .|||..:..|:..:..:|:.:
Zfish   553 -RLTWYTRFDAVIESEEVVSSELYTIDNDIKVRE 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	129/589 (22%)
slc5a11	NP_001007301.1	SLC5sbd_SGLT6	28..668	CDD:271381	144/654 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580133
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740