Protein Alignment CG42235 and slc5a1

DIOPT Version :9

• Sequence 1: NP_651446.2
• Gene: CG42235 / 43136
• FlyBaseID: FBgn0250757
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_956975.1
• Gene: slc5a1 / 393654
• ZFINID: ZDB-GENE-040426-1524
• Length: 658
• Species: Danio rerio
• Alignment Length: 495
• Identity: 115/495 - (23%)
• Similarity: 206/495 - (41%)
• Gaps: 80/495 - (16%)

  Fly   158 YLVGGRQMKVFPVALSLVASFVS-----GISLLGTSTEIYVYGTQYAFILVTLAISGAISWYIFL 217
            :.:.||.|..:|:..||.||.:.     ||:..|.:..|.:.|.::..::|.:.:.     ::|:
Zfish    58 FFLAGRSMVWWPIGASLFASNIGSGHFVGIAGTGAAAGIAIGGFEWNALVVVIILG-----WLFV 117

  Fly   218 PVFCNLQLTSTYEYFERRF-DRRVRIFGS----CLFVVMNILWQPICIYVPALTLNQVSGISVSK 277
            |::....:.:..||.::|| .:|:||:.|    ||:|...|   ...::..|:.:||..|:::..
Zfish   118 PIYIKAGVVTMPEYLKKRFGGQRIRIYLSVLSLCLYVFTKI---SADMFAGAIFINQALGLNIYL 179

  Fly   278 IVPVTSFICILYTSVGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLDLGGLSVVLDHNRQYDRLVG 342
            .|.:...|..|||..||:..|::||.:|..:|:....|::......:||          |:....
Zfish   180 AVVILLLITALYTVTGGLAAVIYTDTLQTIIMVVGSFILMGFAFNKVGG----------YENFRD 234

  Fly   343 PDMTFDP------------TARMGVFALFVG---------GALFKLQANG-----INQAIVQRYL 381
            ..||..|            |.|...|.:|..         |.||.|....     .:|.||||.|
Zfish   235 SYMTAIPSVIGTNISESCYTPRADSFHIFRDPINGDLPWPGLLFGLTIQAGWYWCTDQVIVQRCL 299

  Fly   382 TLPNNKDVKKALVLSLIGF-----MFVMLM------CVYIGLLAFAEFYHCDPITTGLARAKDQV 435
            :..|...||...:  |.|:     ||:|:.      .:|...:|..:...|..:........:..
Zfish   300 SAKNLSHVKAGCI--LCGYLKLLPMFLMVFPGMISRVLYPDEIACVDPDECKAVCGAEVGCTNIA 362

  Fly   436 IPLYVVKNVGHIPGLVGLFVAGVFSAALSSLSTALNSLSGVILTDFVEPFRKKPLTERQTAYLLR 500
            .|..||..:.:  ||.||.::.:.::.:|||::..||.|.:...|.....|.|   .::...::.
Zfish   363 YPKLVVDLMPN--GLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYTKIRPK---AKEKELMIA 422

  Fly   501 G---VVISFGLISMASVPIVQ--RLGLVMQLSSTVAAITCGPLLGAFSVGMLLPFVKTESLLTGI 560
            |   :::..| ||:|.:||||  :.|.:.....::.:....|:...|::.:....|.......|:
Zfish   423 GRLFMLLLIG-ISIAWIPIVQTAQSGQLFDYIQSITSYLAPPIAAVFALAIFCKRVNEPGAFYGL 486

  Fly   561 SCASSFTAYIVVRAQIAIFTGSLTFPAK-PVSIQDCDYTF 599
             |.........:..:.|..|||...|:. |..|....|.:
Zfish   487 -CVGLLVGLARMITEFAYGTGSCVNPSNCPTIICGVHYLY 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	115/495 (23%)
slc5a1	NP_956975.1	SLC5sbd_SGLT1	27..658	CDD:271379	115/495 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580127
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740