Protein Alignment CG42235 and slc5a12

DIOPT Version :9

• Sequence 1: NP_651446.2
• Gene: CG42235 / 43136
• FlyBaseID: FBgn0250757
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_956662.1
• Gene: slc5a12 / 393339
• ZFINID: ZDB-GENE-040426-1343
• Length: 623
• Species: Danio rerio
• Alignment Length: 598
• Identity: 187/598 - (31%)
• Similarity: 308/598 - (51%)
• Gaps: 66/598 - (11%)

  Fly    97 QALQHFGIVDYLVFIAMLAVCAVIGFYFGFIEKKQKKQKLAGKDGGGAAGVEERRGSEALDYLVG 161
            :.:..|...||:||..:..|.:.||.:|                     .::||..:.:.::|||
Zfish     2 ETVGRFQAGDYVVFACLFVVSSGIGVFF---------------------AIKERNKAPSKEFLVG 45

  Fly   162 GRQMKVFPVALSLVASFVSGISLLGTSTEIYVYGTQYAFILVTLAISGAISWYIFLPVFCNLQLT 226
            ||||...||||||.|||:|.::::|...::|.:|..|....|........:..:|||||....:|
Zfish    46 GRQMSCGPVALSLTASFMSAVTVIGAPADVYRFGASYVIFGVAYTFVVFFTAELFLPVFYRSGIT 110

  Fly   227 STYEYFERRFDRRVRIFGSCLFVVMNILWQPICIYVPALTLNQVSGISVSKIVPVTSFICILYTS 291
            |||||.|.||.:.||:..:.::::..||:..:.:|.|||.||||:|..:...:..|..:|..|.:
Zfish   111 STYEYLELRFCKLVRVAATLIYIIQTILYTGVVVYAPALALNQVTGFDLWGSIFATGIVCTFYCT 175

  Fly   292 VGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLDLGGLSVVLDHNRQYDRLVGPDMTFDPTARMGVF 356
            :||:|.|||||..|..||:...|.|:|:|:...||:..|...:|...||...|....|..|...:
Zfish   176 LGGLKAVVWTDAFQMVVMVVGFLTVLIQGSSRAGGIENVWSTSRTGGRLQVFDFDVSPLRRHTFW 240

  Fly   357 ALFVGGALFKLQANGINQAIVQRYLTLPNNKDVKKALVLSLIGFMFVMLMCVYIGLLAFAEFYHC 421
            .|.|||....|...|:||:.:||.::.......:.||.|:|:|...::...|..||:.::.:.||
Zfish   241 TLSVGGTFTWLGIYGVNQSTIQRCISCKTEGHARWALYLNLLGLWIILFCAVVSGLIMYSYYSHC 305

  Fly   422 DPITTGLARAKDQVIPLYVVKNVGHIPGLVGLFVAGVFSAALSSLSTALNSLSGVILTDFVE--- 483
            ||.::||..|.||::|.:|::.:|..|||.|||||..||..||:::.::|:|:.|:..|||.
Zfish   306 DPWSSGLISAPDQLMPYFVMEILGAFPGLPGLFVACAFSGTLSTVAASINALATVMYEDFVSQCF 370

  Fly   484 PFRKKPLTERQTAYLLRGVVISFGLISMASVPIVQRLGLVMQLSSTVAAITCGPLLGAFSVGMLL 548
            |    .|:.|..:::.:.:.::||:...........:|.::|.:.::..:..||:||.||:|:|.
Zfish   371 P----DLSNRAASWISKALCVAFGVACTTMAVAASYMGGIVQAALSIHGMCGGPVLGLFSLGILF 431

  Fly   549 PFVKTESLLTGISCASSFTAYIVVRAQIAIFTGSLTFPAK-------PVSIQDCDYT---FDLPA 603
            ||...:..:.|:....|.:.::.|        |:..:||.       .::...|:.|   |:
Zfish   432 PFTNLKGAVGGLIVGISLSFWVGV--------GAFIYPAPSNNTHALELNTAGCNITAAAFE--- 485

  Fly   604 NWNATTTATPTESTS------HGIHEISFLWYTAVGSVGTVLGSLLATLYFGRQDPRVVD----- 657
                .|:||.|:.||      ...:.:|:|:|:|||.:|||...||.||..|..||:::.
Zfish   486 ----PTSATVTQLTSDRNWLADSWYSMSYLYYSAVGFIGTVAAGLLITLLTGPMDPKLLKPGMTR 546

  Fly   658 --KELISPVLRKF 668
              ||::.....||
Zfish   547 SVKEVMCFCTEKF 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	177/559 (32%)
slc5a12	NP_956662.1	SLC5sbd_SMCT2	4..533	CDD:212089	180/568 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580130
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1180002at2759
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.950