DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42235 and SPBPB8B6.02c

DIOPT Version :9

Sequence 1:	NP_651446.2	Gene:	CG42235 / 43136	FlyBaseID:	FBgn0250757	Length:	698	Species:	Drosophila melanogaster
Sequence 2:	NP_001018763.1	Gene:	SPBPB8B6.02c / 3361185	PomBaseID:	SPBPB8B6.02c	Length:	673	Species:	Schizosaccharomyces pombe

Alignment Length:	526	Identity:	116/526 - (22%)
Similarity:	199/526 - (37%)	Gaps:	117/526 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 YLVGGRQMKVFPVALSLVASFVSGISLLGTSTEIYVYGTQYAFILVTLAISGAISWYIFLPVFCN 222
            :....|.:|...::.|.|:::....:||.:....|.||....|:   ..:.|.|...:||  |..
pombe    45 FSTASRSVKSGLISSSTVSAWTWPATLLSSGAWSYTYGIMGGFM---YGVGGTIQITLFL--FLA 104

  Fly   223 LQLT-------STYEYFERRFDRRVRIFGSCLF----VVMNILWQPICIYVPALTLNQVSGISVS 276
            :|:.       :..|.|..||.:    .|.|::    :..|:|...:.:...:...:..:|::..
pombe   105 IQIKKKAPAAHTVSECFFIRFGK----LGHCVYLFYCISTNVLVSSLLLLGGSQGFSSTTGMNTV 165

  Fly   277 KIVPVTSFICILYTSVGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLDLGGLSVVLDHNRQYDRLV 341
            ....:.....::||::||:|....:|.|. ||||  .:|:|:.........|::....:.||.|.
pombe   166 AACFLLPLGVMVYTTLGGLKATFISDWIH-TVMI--YIILIVTCYTVYCSSSLIGSPAKMYDMLK 227

  Fly   342 GPDMTFDPTARMG------------VFALFVGGALFKLQANGINQ--------AIVQRYL----- 381
            .....:..|....            .:::.:||........|.:|        ::.|.||
pombe   228 EVQEVYPATGGQSYLSFKNSEMMYLTWSVMIGGLSSVFGDPGYSQRAIASDAKSVFQGYLMGGLC 292

  Fly   382 ------TLPNNKDVK-KALVLSLIGFMFVMLMCVYIGLLAFAEFYHCDPITTGLARAKDQVIPLY 439
                  .|.::..:. :||:|:       .....|..:|:..|.....|:..|:|.
pombe   293 WWIIPMALGSSAGLACRALLLN-------PASVTYPNVLSSVEISSGLPVIYGMAS--------- 341

  Fly   440 VVKNVGHIPGLVGLFVAGVFSAALSSLSTALNSLSGVILTDFVEPFRKKPLTERQ---TAYLLRG 501
            :....|...|||.||:     :..|:.|..|.:.|.|...|....:.......:|   ||:|
pombe   342 IFGKSGAAAGLVMLFM-----SITSATSAELIAFSSVTTYDIFRAYINPAANGKQLVRTAHL--- 398

  Fly   502 VVISFGL-ISMASVP----------IVQRLGLVMQLSSTVAAIT-C--GPLLGAFSVGMLLPFVK 552
            .||.|.| |...||.          ::..||::  |:..|:|:| |  ...:..||:.:..||
pombe   399 SVIGFSLFIGALSVGFNYAGVTAGWLLTFLGII--LTPEVSAVTLCLFWNKMTRFSLVVGAPF-- 459

  Fly   553 TESLLTGISC--AS--SFTAYIV----VRAQIAIFTGSL-TFPAKPVSIQDCDY------TFDLP 602
              ..:||:.|  ||  ||...||    |....|.|.|:: :..:.|:.|....|      ||||.
pombe   460 --GTITGVVCWLASTYSFCDGIVNKDTVMTSKACFVGNIVSMASSPLYIVLLSYIWPDKETFDLN 522

  Fly   603 ANWNAT 608
            ...|.|
pombe   523 QFRNIT 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	116/526 (22%)
SPBPB8B6.02c	NP_001018763.1	SLC5sbd_DUR3	11..513	CDD:271370	110/509 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	74	1.000	Domainoid score	I2508
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1855
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
TreeFam	0	0.000	Not matched by this tool.
	4	3.950