Protein Alignment CG42235 and Slc5a6

DIOPT Version :9

• Sequence 1: NP_651446.2
• Gene: CG42235 / 43136
• FlyBaseID: FBgn0250757
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001171092.1
• Gene: Slc5a6 / 330064
• MGIID: 2660847
• Length: 634
• Species: Mus musculus
• Alignment Length: 620
• Identity: 209/620 - (33%)
• Similarity: 310/620 - (50%)
• Gaps: 77/620 - (12%)

  Fly    68 AYTPTPTPTQSASPSLEDGEEKLSVKDLSQALQHFGIVDYLVFIAMLAVCAVIGFYFGFIEKKQK 132
            |.|..|..|.|.|               |.|:..|.:|||:||..:|.:..|||.|...
Mouse     4 ASTAAPFHTTSGS---------------SGAISTFSVVDYVVFGLLLVLSLVIGLYHAC------ 47

  Fly   133 KQKLAGKDGGGAAGVEERRGSEALDYLVGGRQMKVFPVALSLVASFVSGISLLGTSTEIYVYGTQ 197
                   .|.|...|.|        .|:..|:|...||||||:|:|.|.:::||...||:.:|||
Mouse    48 -------RGWGHHTVGE--------LLMADRKMGCLPVALSLLATFQSAVAILGAPAEIFRFGTQ 97

  Fly   198 YAFILVTLAISGAISWYIFLPVFCNLQLTSTYEYFERRFDRRVRIFGSCLFVVMNILWQPICIYV 262
            |.|:..:..:...|..:||:|||..|.|||.|||.|.||::.|||.|:..|:...:::..:.:|.
Mouse    98 YWFLGCSYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFNKAVRICGTVTFIFQMVIYMGVALYA 162

  Fly   263 PALTLNQVSGISVSKIVPVTSFICILYTSVGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLDLGGL 327
            |:|.||.|:|..:...|.....:|.:||::||:|.|:||||.|..||....|:|||.|...:|||
Mouse   163 PSLALNAVTGFDLWLSVLALGIVCNIYTALGGLKAVIWTDVFQTLVMFLGQLVVIIVGAARVGGL 227

  Fly   328 SVVLDHNRQYDRLVGPDMTFDPTARMGVFALFVGGALFKLQANGINQAIVQRYLTLPNNKDVKKA 392
            ..|.:...|:..:.|.::..||..|...:.|..||....|...|:|||.|||||    :...::|
Mouse   228 GHVWNVTSQHGLISGINLDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQRYL----SSHSERA 288

  Fly   393 LVLSLIGF----MFVMLMCVYIGLLAFAEFYHCDPITTGLAR-AKDQVIPLYVVKNVGHIPGLVG 452
            .|||....    ...:.|...|||:.|| :|:...::..|.: |.||::..:|:..:..:|||.|
Mouse   289 AVLSCYAVFPCQQVALCMSCLIGLVMFA-YYNMYSMSPELKQAAPDQLVLYFVMDLLKDMPGLPG 352

  Fly   453 LFVAGVFSAALSSLSTALNSLSGVILTDFVEPFRKKPLTERQTAYLLRGVVISFGLISMASVPIV 517
            ||||.:||.:||::|:|.|||:.|.:.|.::|:..: |||.:...|.||:..::||:.:....|.
Mouse   353 LFVACLFSGSLSTISSAFNSLATVTMEDLIQPWFPQ-LTETRAIMLSRGLAFAYGLVCLGMAYIS 416

  Fly   518 QRLGLVMQLSSTVAAITCGPLLGAFSVGMLLPFVK----TESLLTGISCASSF-TAYIVVRAQIA 577
            ..||.|:|.:.::..:..|||||.|.:|:..|...    ...||||::.|... ...||.|...|
Mouse   417 SHLGSVLQAALSIFGMVGGPLLGLFCLGLFFPCANPLGAIVGLLTGLTMAFWIGIGSIVSRMSSA 481

  Fly   578 I----FTGSLTFPAKPVSIQDCDYTFDLPANWN--ATTTATP-TESTSHGI---HEISFLWYTAV 632
            :    ..||.:|               ||||..  |.||..| |.|...|:   :.:|:|||:|.
Mouse   482 VAPPPLNGSSSF---------------LPANVTVAAVTTVMPSTLSKPTGLQHFYSLSYLWYSAH 531

  Fly   633 GSVGTVLGSLLATLYFGRQDPRVVDKELISPVLRK 667
            .|...::..|:.:|..|....|.::...|.|||.|
Mouse   532 NSTTVIVVGLIVSLLTGGMRGRSLNPGTIYPVLPK 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	192/560 (34%)
Slc5a6	NP_001171092.1	SLC5-6-like_sbd	23..548	CDD:320982	194/566 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820