Protein Alignment CG42235 and Slc5a4

DIOPT Version :9

• Sequence 1: NP_651446.2
• Gene: CG42235 / 43136
• FlyBaseID: FBgn0250757
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001099853.1
• Gene: Slc5a4 / 294341
• RGDID: 1306923
• Length: 671
• Species: Rattus norvegicus
• Alignment Length: 736
• Identity: 156/736 - (21%)
• Similarity: 280/736 - (38%)
• Gaps: 204/736 - (27%)

  Fly    25 TTVANAIAKTVAVISSTVSTSSTTGATSTISTSSSTPTTSTTFAYTPTPTPTQSASPSLEDGEEK 89
            |.:..|:|.|     ::||||:.:...|::|.:.:.|.
  Rat     6 TALPRAMAST-----ASVSTSTGSSELSSLSDNINNPA--------------------------- 38

  Fly    90 LSVKDLSQALQHFGIVDYLVFIAMLAVCAVIGFYFGFIEKKQKKQKLAGKDGGGAAGVEERRGSE 154
                |:|.      ||.|.|.:..:.|.|::         |..:..:.|
  Rat    39 ----DISV------IVIYFVVVMAVGVWAMV---------KTNRSTVGG---------------- 68

  Fly   155 ALDYLVGGRQMKVFPVALSLVASFVS-----GISLLGTSTEIYVYGTQ---YAFILVTLAISGAI 211
               :.:.||.|..:|:..||.||.:.     |::..|.:|.|.|...:   :|.:||       :
  Rat    69 ---FFLAGRSMTWWPMGASLFASNIGSGHFVGLAGTGAATGIAVTAFESHSFALLLV-------L 123

  Fly   212 SWYIFLPVFCNLQLTSTYEYFERRF-DRRVRIFGS--CLFVVMNILWQPICIYVPALTLNQVSGI 273
            .|: |:|::....:.:..||..:|| .:|::|:.|  .||:.: ||.....|:..|:.:....|:
  Rat   124 GWF-FVPIYIKAGVMTMPEYLRKRFGGKRLQIYLSVLSLFICV-ILTISADIFSGAIFIKLALGL 186

  Fly   274 SVSKIVPVTSFICILYTSVGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLDLGGLSVVLDHNRQYD 338
            .:...:.:...|..::|..||:..|::||.:|..:|:....|::|...:::||..   ....:|.
  Rat   187 DLYLAIFILLAITAVFTITGGLASVIYTDTLQAIIMLVGSFILMIYAFVEVGGYE---SFTEKYM 248

  Fly   339 RLV-----GPDMTFDP---TARMGVFALF----VG-----GALFKLQANG-----INQAIVQRYL 381
            ..:     |.::|..|   |.:...|.:|    .|     |..|.:....     |||.||||.|
  Rat   249 NAIPSVVEGDNLTISPKCYTPQPDSFHIFRDAVTGDIPWPGTAFGMPITALWYWCINQVIVQRCL 313

  Fly   382 TLPNNKDVKKALVLSLIGFM-----FVMLMCVYIGLLAFAEFYHCDPITTGLARAKDQVIPLYVV 441
            ...|...||.|.:  :.|::     |.|:|...|..:.:.:...|             |:|...|
  Rat   314 CGKNMSHVKAACI--VCGYLKLLPIFFMVMPGMISRILYTDMVAC-------------VVPSECV 363

  Fly   442 KNVG----------------HIP-GLVGLFVAGVFSAALSSLSTALNSLSGVILTDFVEPFRKKP 489
            |..|                .:| ||.||.::.:.::.:|||::..||.|.:...|.....|||
  Rat   364 KQCGVDVGCTNYAYPMLVLKLMPMGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDLYTKIRKK- 427

  Fly   490 LTERQTAYLLRGVVISFGLISMASVPIVQ--RLGLVMQLSSTVAAITCGPLLGAFSVGMLLPFVK 552
            .:||:.....|..|....:.|:..||||:  :.|.::..:..:::....|:...|.|.:....|.
  Rat   428 ASERELLIAGRLFVSVLIVTSILWVPIVEVSQGGQLIHYTEAISSYLGPPIAAVFLVAIFCKRVN 492

  Fly   553 TESLLTGISCASSFTAYIVVRAQIAIFTGSLTFPAK-PVSIQDCDYTFDLPANWNATTTATPTES 616
            .:....|: ........|.:.|:.:..|||...|:. |..|  |
  Rat   493 EQGAFWGL-MVGLVLGLIRMIAEFSYGTGSCLAPSSCPKVI--C--------------------- 533

  Fly   617 TSHGIHEISFLWYTAVGSVGTVLGSLLATLYFGRQDPRVVDKELISPVLRKFWYGKYESVASEEK 681
               |:|   :|:|..:....::| .:|...|..:..|.|       .:.|..|     |:.:.|:
  Rat   534 ---GVH---YLYYAIILFFVSIL-VILGVSYLTKPIPDV-------HLYRLCW-----SLRNSEE 579

  Fly   682 NNFNL-----HESETQLKLEQ 697
            ...:|     .|:|...:.|:
  Rat   580 ERIDLDAEDREENEADARTEE 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	131/598 (22%)
Slc5a4	NP_001099853.1	SLC5-6-like_sbd	38..671	CDD:294310	145/699 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340292
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740