Protein Alignment CG42235 and Slc5a11

DIOPT Version :9

• Sequence 1: NP_651446.2
• Gene: CG42235 / 43136
• FlyBaseID: FBgn0250757
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001093952.2
• Gene: Slc5a11 / 252854
• RGDID: 621410
• Length: 673
• Species: Rattus norvegicus
• Alignment Length: 663
• Identity: 147/663 - (22%)
• Similarity: 268/663 - (40%)
• Gaps: 144/663 - (21%)

  Fly    64 STTFAYTPTPTPTQSASPSLEDGEEKLSVKDLSQALQHFGIVDYLVFIAMLAVCAVIGFYFGFIE 128
            |||.:..|.|:....|.|     ::.:...|:        :|..|.|:.:|||    |.:   ..
  Rat     3 STTSSPQPPPSDALEAFP-----QKSMEPADI--------VVLVLYFLFVLAV----GLW---ST 47

  Fly   129 KKQKKQKLAGKDGGGAAGVEERRGSEALDYLVGGRQMKVFPVALSLVASFV-SG--ISLLGTSTE 190
            .:.|:..:.|                   |.:.|..|..:||..||.||.| ||  |.|.|:...
  Rat    48 VRTKRDTVKG-------------------YFLAGGDMVWWPVGASLFASNVGSGHFIGLAGSGAA 93

  Fly   191 IYV----YGTQYAFILVTLAISGAISWYIFLPVFCNLQLTSTYEYFERRF-DRRVRIFGSCLFVV 250
            :.:    |.....|.::.||       :||||::...|:|:..||..||| ..|:.|..:.|::.
  Rat    94 VGISVAAYELNGLFSVLMLA-------WIFLPIYIAGQVTTMPEYLRRRFGGSRIPITLAVLYLF 151

  Fly   251 MNILWQ-PICIYVPALTLNQVSGISVSKIVPVTSFICILYTSVGGIKGVVWTDVIQGTVMIGSML 314
            :.|..: .:.:|..|:.:.|...:.:...:.....:..|||..||:..|::||.:|..:|:....
  Rat   152 IYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAVTALYTVAGGLAAVIYTDALQTVIMLIGAF 216

  Fly   315 IVIIKGTLDLGGLS-------VVLDHNRQYDRLVGPDMTFDPTARMGVFALFVG---------GA 363
            |::......:||:.       :.|..||..:...|       ..|...|.:|..         |.
  Rat   217 ILMGYSFAAVGGMEGLKDQYFLALASNRSENSSCG-------LPREDAFHIFRDPLTSDLPWPGI 274

  Fly   364 LFKLQANGI-----NQAIVQRYLTLPNNKDVK---------KALVLSLIGFMFVMLMCVYIGLLA 414
            ||.:....:     :|.||||.|...|....|         |.|.|.|:.|..::...::...:|
  Rat   275 LFGMSIPSLWYWCTDQVIVQRSLAAKNLSHAKGGSLMAAYLKVLPLFLMVFPGMVSRILFPDQVA 339

  Fly   415 FAEFYHCDPITTGLARAKDQVIPLYVVKNVGHIP-GLVGLFVAGVFSAALSSLSTALNSLSGVIL 478
            .|....|..:.:..:...|...|..|::   .:| ||.||.:|.:.:|.:|||::..||.|.:..
  Rat   340 CAHPDICQRVCSNPSGCSDIAYPKLVLE---LLPTGLRGLMMAVMVAALMSSLTSIFNSASTIFT 401

  Fly   479 TDFVEPFRKKPLTERQTAYLLRGVVISFGLISMASVPIVQ-----RLGLVMQLSSTVAAITCGPL 538
            .|.....|.: .:||:...:.|..|::..|:|:..:|:||     :|.:.:|   ::::....|:
  Rat   402 MDLWHHIRPR-ASERELMIVGRVFVLALVLVSILWIPVVQASQGGQLFIYIQ---SISSYLQPPV 462

  Fly   539 LGAFSVGMLLPFVKTESLLTGISCASSFTAYIVVRAQIAIFTGSLTFPAKPVSIQD-CDYTFDLP 602
            ...|.:|........:...:|:.              :.:..|.:......|.:|. ||...|.|
  Rat   463 AVVFIMGCFWKRTNEKGAFSGLI--------------LGLLLGLVRLILDFVYVQPRCDQPDDRP 513

  Fly   603 ANWNATTTATPTESTSHGIHEISFLWYTAVGSVGTVLGSLLATLYFGRQDPRVVDKELISPVLRK 667
            |                .:.::.:|:::.:.|..|::  .:.|:.:..:.|   .||::|   |.
  Rat   514 A----------------VVKDVHYLYFSMILSSTTLI--TVFTVSWFTETP---SKEMVS---RL 554

  Fly   668 FWYGKYESVASEE 680
            .|:.::|.||.::
  Rat   555 TWFTRHEPVAQKD 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	129/586 (22%)
Slc5a11	NP_001093952.2	SLC5-6-like_sbd	28..673	CDD:294310	140/633 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340301
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840