Protein Alignment CG42235 and SLC5A9

DIOPT Version :9

• Sequence 1: NP_651446.2
• Gene: CG42235 / 43136
• FlyBaseID: FBgn0250757
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: XP_011539226.1
• Gene: SLC5A9 / 200010
• HGNCID: 22146
• Length: 719
• Species: Homo sapiens
• Alignment Length: 667
• Identity: 136/667 - (20%)
• Similarity: 243/667 - (36%)
• Gaps: 192/667 - (28%)

  Fly    76 TQSASPSLEDGEEKLSVKDLSQALQHFGIVDYLVFIAMLAVCAVIGFYFGFIEKKQKKQKLAGKD 140
            |::|.....|....|...|:|.      :|.|.||:..:.:.:.|....|.|
Human    19 TETAPHIALDSRVGLHAYDISV------VVIYFVFVIAVGIWSSIRASRGTI------------- 64

  Fly   141 GGGAAGVEERRGSEALDYLVGGRQMKVFPVALSLVASFV-SG--ISLLGTST------------- 189
             ||              |.:.||.|..:|:..||::|.| ||  |.|.||..
Human    65 -GG--------------YFLAGRSMSWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNM 114

  Fly   190 ----------------------------------------------EIYVYG---------TQYA 199
                                                          .:|:..         :|..
Human   115 RKSRSGGDRGIHPRSHGRTGVRSQVSYFSVRGPPTAQHCLWVGSRPSVYIQDLDTFFFSPLSQAT 179

  Fly   200 FILVTLAISGAISWYIFLPVFCNLQLTSTYEYFERRF-DRRVRIFGSCLFVVMNILWQ-PICIYV 262
            ::|:      |:.| :|:||:....:.:..:|.::|| .:|::::.|.|.:::.|..: ...|:.
Human   180 WLLL------ALGW-VFVPVYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFS 237

  Fly   263 PALTLNQVSGISVSKIVPVTSFICILYTSVGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLDLG-- 325
            .||.:....|.::.....:...:..:||..||:..|::||.:|..:|:|..|:::..|..|:|
Human   238 GALFIQMALGWNLYLSTGILLVVTAVYTIAGGLMAVIYTDALQTVIMVGGALVLMFLGFQDVGWY 302

  Fly   326 -GLSVVLDHNRQYDRLVGPDMTFDPTA----RMGVFALFVGGALFKLQANGINQAIVQRYLTLPN 385
             ||      .::|.:.: |::|...|.    |...|.:.            .:..||||.|:..:
Human   303 PGL------EQRYRQAI-PNVTVPNTTCHLPRPDAFHIL------------RDPVIVQRSLSAKS 348

  Fly   386 NKDVKKALVLSLIGFMFV--MLMCVYIGLLAFAEFYH---------CDPITTGLARAKDQVIPLY 439
            ....|...||.  |::.:  |...|..|:::.|.|..         |..|........:...|..
Human   349 LSHAKGGSVLG--GYLKILPMFFIVMPGMISRALFPDEVGCVDPDVCQRICGARVGCSNIAYPKL 411

  Fly   440 VVKNVGHIP-GLVGLFVAGVFSAALSSLSTALNSLSGVILTDFVEPFRKKPLTERQTAYLLRGVV 503
            |   :..:| ||.||.:|.:.:|.:|||::..||.|.:...|..:.||:|. ||::...:.|..|
Human   412 V---MALMPVGLRGLMIAVIMAALMSSLTSIFNSSSTLFTIDVWQRFRRKS-TEQELMVVGRVFV 472

  Fly   504 ISFGLISMASVPIVQ--RLGLVMQLSSTVAAITCGPLLGAFSVGMLLPFVKTESLLTGISCASSF 566
            :...:||:..:||:|  ..|.:......|.:....|:...|.:.:....|.......|:    .|
Human   473 VFLVVISILWIPIIQSSNSGQLFDYIQAVTSYLAPPITALFLLAIFCKRVTEPGAFWGL----VF 533

  Fly   567 TAYIVVRAQIAIFTGSLTFPA--------KPVSIQD----------CDYTFDLPANWNATTTATP 613
            ...:.:...|..|    ::||        :|..::|          |..|..:....:..||..|
Human   534 GLGVGLLRMILEF----SYPAPACGEVDRRPAVLKDFHYLYFAILLCGLTAIVIVIVSLCTTPIP 594

  Fly   614 TESTSHGIHEISFLWYT 630
            .|..:.      ..|:|
Human   595 EEQLTR------LTWWT 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	130/638 (20%)
SLC5A9	XP_011539226.1	SLC5-6-like_sbd	37..719	CDD:294310	132/649 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146431
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740