Protein Alignment CG42235 and SLC5A10

DIOPT Version :9

• Sequence 1: NP_651446.2
• Gene: CG42235 / 43136
• FlyBaseID: FBgn0250757
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: XP_016879680.2
• Gene: SLC5A10 / 125206
• HGNCID: 23155
• Length: 649
• Species: Homo sapiens
• Alignment Length: 649
• Identity: 137/649 - (21%)
• Similarity: 248/649 - (38%)
• Gaps: 159/649 - (24%)

  Fly    91 SVKDLSQALQHFGIVDYLVFIAMLAVCAVIGFYFGFIEKKQKKQKLAGKDGGGAAGVEERRGSEA 155
            |..||........:.|.:|.....|:...:|.:...   :..:..:.|
Human     5 STSDLHTPGTQLSVADIIVITVYFALNVAVGIWSSC---RASRNTVNG----------------- 49

  Fly   156 LDYLVGGRQMKVFPVALSLVAS------FVSGISLLGTSTEIYVYGTQYAFILVTLAISGAISWY 214
              |.:.||.|..:|:..||.||      |: |::..|.:..:.|.|.::....|.||::     :
Human    50 --YFLAGRDMTWWPIGASLFASSEGSGLFI-GLAGSGAAGGLAVAGFEWNATYVLLALA-----W 106

  Fly   215 IFLPVFCNLQLTSTYEYFERRF-DRRVRIFGSCLFVVMNILWQ-PICIYVPALTLNQVSGISVSK 277
            :|:|::.:.::.:..||.::|: .:|:|::.|.|.:::::..: .:.:|..||.::...|.:...
Human   107 VFVPIYISSEIVTLPEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYL 171

  Fly   278 IVPVTSFICILYTSVGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLDLGGLSVVLDHNRQYDRLVG 342
            ...:|..|..|||..||:..|::||.:|..:|:...:|:.||....:||...:   ...|.:.:
Human   172 STILTLGITALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQL---EAAYAQAI- 232

  Fly   343 PDMTFDPTA----RMGVFALF----VG-----GALFKLQANG-----INQAIVQRYLTLPNNKDV 389
            |..|...|.    |.....:|    .|     |..|.|....     .:|.||||.|:..:....
Human   233 PSRTIANTTCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHA 297

  Fly   390 KKALVLSLIGFMFVMLMCVYIGLLAFAEF----YHCDPITTGLARAKDQ--VIPLYVVK------ 442
            |...:|:....|..|.:.:..|:::.|.|    .:.:.....::|..|.  |:|...::
Human   298 KAGSILASYLKMLPMGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEV 362

  Fly   443 ---NVGH-------IP-GLVGLFVAGVFSAALSSLSTALNSLSGVILTDFVEPFRKK-------- 488
               |:.:       :| ||.||.:|.:.:|.:|||::..||.|.:...|.....|.:
Human   363 GCSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLL 427

  Fly   489 ---------------------PLTERQTAYLLRGVVISFGL-------ISMASVPIVQ-----RL 520
                                 |.|.....|||..||:...|       :|:|.:|::|     :|
Human   428 VGRTGIPSTPPAPQSRLSFLLPETPPLERYLLGLVVMDLWLVIVALIGVSVAWIPVLQDSNSGQL 492

  Fly   521 GLVMQ--LSSTVAAITCGPLLGAF--------------------SVGMLLPFVK---------TE 554
            .:.||  .||....:|...:||.|                    :..::|.|:.         |.
Human   493 FIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTR 557

  Fly   555 SLLTGISCASSFTAYIVVRAQIAIFTGSLTFPAKPVSIQDCDYTF-----DLPANWNATTTATP 613
            ..:.|......|...:...:...:..|||..| .|.|:|..:.|:     |:|....|....||
Human   558 PAVLGSIHYLHFAVALFALSGAVVVAGSLLTP-PPQSVQIENLTWWTLAQDVPLGTKAGDGQTP 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	134/635 (21%)
SLC5A10	XP_016879680.2	SLC5-6-like_sbd	17..649	CDD:320982	134/637 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146492
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740