Protein Alignment kumpel and slc5a9

DIOPT Version :10

• Sequence 1: NP_651446.2
• Gene: kumpel / 43136
• FlyBaseID: FBgn0250757
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: XP_002931459.2
• Gene: slc5a9 / 100495397
• XenbaseID: XB-GENE-940879
• Length: 679
• Species: Xenopus tropicalis
• Alignment Length: 535
• Identity: 131/535 - (24%)
• Similarity: 227/535 - (42%)
• Gaps: 118/535 - (22%)

  Fly    80 SPSLEDGEEKLSVKDLSQALQHFGIVDYLVFIAMLAVCAVIGFYFGFIEKKQKKQKLAGKDGGGA 144
            :||.::..||..|.|:      ..:|.|.||:..:.:.:.|             :...|..||
 Frog     7 APSDDNQPEKFGVPDI------IVVVVYFVFVLGVGIWSSI-------------RASRGTVGG-- 50

  Fly   145 AGVEERRGSEALDYLVGGRQMKVFPVALSLVASFV-SG--ISLLGTSTE--IYVYGTQY--AFIL 202
                         |.:.||.|..:|:..||::|.| ||  |.|.|::..  :.|.|.::  :::|
 Frog    51 -------------YFLAGRSMTWWPIGASLMSSNVGSGLFIGLAGSAAAGGLAVGGFEWNASWVL 102

  Fly   203 VTLAISGAISWYIFLPVFCNLQLTSTYEYFERRF-DRRVRIFGSCLFVVMNILWQ-PICIYVPAL 265
            |      |:.| ||:||:....:.:..||.::|| .:|:||:.|.|.:::.|..: ...||..||
 Frog   103 V------ALGW-IFVPVYIASGVVTMPEYLKKRFGGKRIRIYISVLSLILYIFTKISTDIYSGAL 160

  Fly   266 TLNQVS---GISVSKIVPVTSFICILYTSVGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLDLG-- 325
            .: |||   .|.:|.::.:.  :..:||..||:..|::||.:|..:|:....:::......:|
 Frog   161 FI-QVSLGWNIYLSTVILLA--VTAIYTIAGGLTAVIYTDTLQTVIMVAGAFVLMFISFEKIGWY 222

  Fly   326 -GLSVVLDHNRQYDRLVGPDMTFDPTA----RMGVFALF----VG-----GALFKLQANG----- 371
             ||      .::|...: |.:|...|.    |...|.:|    .|     |.:|.|....
 Frog   223 PGL------EQKYMEAI-PKITVANTTCHLPRADAFHIFRDPLTGDLPWPGLIFGLTVLATWVWC 280

  Fly   372 INQAIVQRYLTLPNNKDVKKALVLSLIGFMFV--MLMCVYIGLLAFAEFYHCDPITTGLARAKDQ 434
            .:|.||||.|...|....|...||.  |::.:  |...|..|:::.|.|    |...|.
 Frog   281 TDQVIVQRSLAAKNLSHAKGGSVLG--GYLKILPMFFVVLPGMISKALF----PDEVGC------ 333

  Fly   435 VIPLYVVK---------NVGH-------IP-GLVGLFVAGVFSAALSSLSTALNSLSGVILTDFV 482
            |.|...:|         |:.:       :| ||.||.:|.:.:|.:|||::..||.|.:...|..
 Frog   334 VDPAECLKYCGVEVSCSNIAYPKLVITLLPVGLKGLMIAVIMAALMSSLTSIFNSASTIFTLDVW 398

  Fly   483 EPFRKKPLTERQTAYLLRGVVISFGLISMASVPIVQ--RLGLVMQLSSTVAAITCGPLLGAFSVG 545
            ...|:. ..|::...:.|..::...:||:..:||:|  ..||:.....:|.:....|:...|.:.
 Frog   399 LRIRRN-AKEQELMIVGRVFILILVVISILWIPIIQAANSGLLFDYMQSVTSYLSPPITAIFILA 462

  Fly   546 MLLPFVKTESLLTGI 560
            :.:..|.......|:
 Frog   463 IFIKRVNEPGAFWGL 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kumpel	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	125/510 (25%)
slc5a9	XP_002931459.2	SLC5sbd_SGLT4	21..679	CDD:271380	126/521 (24%)