Protein Alignment kumpel and slc5a5

DIOPT Version :10

• Sequence 1: NP_651446.2
• Gene: kumpel / 43136
• FlyBaseID: FBgn0250757
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001116937.1
• Gene: slc5a5 / 100144711
• XenbaseID: XB-GENE-486472
• Length: 600
• Species: Xenopus tropicalis
• Alignment Length: 621
• Identity: 185/621 - (29%)
• Similarity: 303/621 - (48%)
• Gaps: 75/621 - (12%)

  Fly    75 PTQ-----SA----SPSLEDGEEKLSVKDLSQALQHFGIVDYLVFIAMLAVCAVIGFYFGFIEKK 130
            |||     ||    ||..|..||.:.:  :.::|. |.:.||.||..||.:...||.::.|....
 Frog    20 PTQHLQHTSASSHRSPDTEIMEEYVPL--VHESLT-FSLWDYGVFATMLIMSTGIGLFYAFSHGG 81

  Fly   131 QKKQKLAGKDGGGAAGVEERRGSEALDYLVGGRQMKVFPVALSLVASFVSGISLLGTSTEIYVYG 195
            ||...                     |:..|||.|...||.|||.|||:|.:.:||...|.|.||
 Frog    82 QKTSD---------------------DFFTGGRSMSAVPVGLSLSASFMSAVQVLGVPAEAYRYG 125

  Fly   196 TQYAFILVTLAISGAISWYIFLPVFCNLQLTSTYEYFERRFDRRVRIFGSCLFVVMNILWQPICI 260
            .::..:.:...::..::.|||:|:|..|.:||||:|.|.||.|.||::|:..|::..:.:..|.|
 Frog   126 VKFLQMCIGQILNSVMTAYIFMPIFYRLGITSTYQYLEMRFSRSVRLYGTIQFLLGTMFYTGIVI 190

  Fly   261 YVPALTLNQVSGISVSKIVPVTSFICILYTSVGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLDLG 325
            |.|||.||||:|:.:...:..|..||..||:|||:|.|:||||.|..||:.....|.|:|...:|
 Frog   191 YAPALILNQVTGLDIWASLFSTGAICTFYTTVGGMKAVIWTDVFQVFVMLSGFFAVAIRGIHLVG 255

  Fly   326 GLSVVLDHNRQYDRLVGPDMTFDPTARMGVFALFVGGALFKLQANGINQAIVQRYLTLPNNKDVK 390
            |.|..::....|.|:...|...||..|...:...:|.....|...|:|||.||||:......:.|
 Frog   256 GFSDAIEVAGNYSRINFGDFDPDPRRRYTFWTFVMGSTFLWLSMYGVNQAQVQRYVACKTENEAK 320

  Fly   391 KALVLSLIGFMFVMLMCVYIGLLAFAEFYHCDPITTGLARAKDQVIPLYVVKNVGHIPGLVGLFV 455
            .|::::.:....::...|..|::.|..:.:|||:..|...|.||.:|.:|::.....||:.|||:
 Frog   321 LAILVNQVALCVIVSSAVTCGIVMFVYYLNCDPLLAGYVSAPDQYMPYFVLEIFDQYPGIPGLFL 385

  Fly   456 AGVFSAALSSLSTALNSLSGVILTDFVEPFRKKP-LTERQTAYLLRGVVISFGLISMASVPIVQR 519
            |..:|..||:.||::|:::.|.:.|.:.|  |.| ::.::...:.:|:.:::| .|..:|..:..
 Frog   386 ACAYSGTLSTASTSINAMAAVTVEDLIRP--KYPNISTKKLTLISKGLSLAYG-CSCITVAALSS 447

  Fly   520 L--GLVMQLSSTVAAITCGPLLGAFSVGMLLPFVKTESLLTGISCASSFTAYIVVRAQI------ 576
            |  |.|:|.|.||..:..|||||||.:||......|..:..|:......:.::.|...|
 Frog   448 LLGGGVLQGSFTVMGVISGPLLGAFMLGMFFASCNTIGVFAGLLVGLVISLWVAVGGTIYPPSAE 512

  Fly   577 ------------AIFTGSLTFPAKPVSIQDCDYTFDLPANWNATTTATPTESTSHGIHEISFLWY 629
                        .::..|......|..:|:..:|.:.||             .:..::.:|:|:|
 Frog   513 MMGVLPTFAEHCPLYNSSKGIIYGPAPVQNITHTLERPA-------------LADDLYALSYLYY 564

  Fly   630 TAVGSVGTVLGSLLATLYFGRQDPRVVDKELISPVL 665
            ..||::.||:..::.:.:.|     ...:|.|:|.|
 Frog   565 GVVGTISTVIIGVIVSKFTG-----PTKRETIAPGL 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kumpel	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	168/561 (30%)
slc5a5	NP_001116937.1	SLC5sbd_NIS	56..587	CDD:271393	169/572 (30%)