Protein Alignment CG42235 and slc5a10

DIOPT Version :9

• Sequence 1: NP_651446.2
• Gene: CG42235 / 43136
• FlyBaseID: FBgn0250757
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: XP_017211446.2
• Gene: slc5a10 / 100007379
• ZFINID: ZDB-GENE-110922-5
• Length: 637
• Species: Danio rerio
• Alignment Length: 665
• Identity: 139/665 - (20%)
• Similarity: 246/665 - (36%)
• Gaps: 182/665 - (27%)

  Fly   100 QHFGIVDYLVFIAMLAVCAVIGFYFGFIEKKQKKQKLAGKDGGGAAGVEERRGSEALDYLVGGRQ 164
            |.|.:.|.:|..|...:...:|.:...   :..:..|:|                   |.:.||.
Zfish    14 QSFSVSDIIVIGAYFLLNVAVGIWSSC---RVSRNTLSG-------------------YFLAGRD 56

  Fly   165 MKVFPVALSLVAS------FVSGISLLGTSTEIYVYGTQYAFILVTLAISGAISWYIFLPVFCNL 223
            |..:|:..||.||      |: |::..|.:..|.|.|.::......||::     ::|:||:.:.
Zfish    57 MAWWPIGASLFASSEGSGLFI-GLAGTGAAGGIAVAGFEWNATYALLALA-----WVFVPVYVSS 115

  Fly   224 QLTSTYEYFERRF-DRRVRIFGSCLFVVMNILWQ-PICIYVPALTLNQVSGISVSKIVPVTSFIC 286
            .:.:..||..||| ..|:|::.|.|.:::::..: ...:|..||.:....|.::.....:...:.
Zfish   116 GIVTMPEYLGRRFGGERIRMYLSALSLLLSVFTKISTDLYSGALFVQVCLGWNLYLSTVLMLVVT 180

  Fly   287 ILYTSVGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLDLGGL----SVVLD------------HNR 335
            .|||..||:..|::||.:|..:||...:|:.|.....:||.    ||.|.            |..
Zfish   181 ALYTIAGGLAAVIYTDTLQTFIMIIGAVILTITAFNKIGGYSNLESVYLQAVPSKIIPNTTCHLP 245

  Fly   336 QYDR-----------LVGPDMTFDPTARMGVFALFVGGALFKLQANGINQAIVQRYLTLPNNKDV 389
            ::|.           |..|.||...|    :.|.:....         :|.||||.|:..:....
Zfish   246 RHDAMHLFRDPVHGDLPWPGMTLGLT----IIATWYWCT---------DQVIVQRSLSAKSLSHA 297

  Fly   390 KKALV----LSLIGFMFVML-----MCVYIGLLAFAEFYHCDPITTGLARAKDQVIPLYVVKNVG 445
            |.|.:    |.|:..||::|     ..:|...:|..:...|..:........:...|..|::.:.
Zfish   298 KGASIFASYLKLLPMMFIILPGMISRALYPDTVACVDPEECVKVCGAEVGCSNIAFPKLVIELMP 362

  Fly   446 HIPGLVGLFVAGVFSAALSSLSTALNSLSGVILTDFVEPFRKKPLTERQTAYLLRGVVISFGLIS 510
              .||.||.:|.:.:|.:|||::..||.|.:...|..:.:| :..:|::...:.|.|.:...:||
Zfish   363 --SGLRGLMIAVMMAALMSSLTSIFNSSSTLFTMDIWKKYR-RGASEKELLLVGRIVTVILVVIS 424

  Fly   511 MASVPIVQRLGLVMQLSSTVAAITCGPLLGAFSVGMLLPFVKTESLLTGISCASSFTAYIVVRAQ 575
            :..:||:|                      :.:.|.|..:::            |.|:|:
Zfish   425 VVWIPILQ----------------------SANSGQLYVYIQ------------SVTSYL----- 450

  Fly   576 IAIFTGSLTFPAKPVSIQDCDYTFDLPANWNATTTATPTESTSHGIHEISFLWYTAVGSVGTVLG 640
                       |.||:.     .|.:...|..|             :|....|..   .||.|:|
Zfish   451 -----------APPVTA-----IFVMAVFWKRT-------------NEAGAFWGL---MVGLVVG 483

  Fly   641 SLLATLYFGRQDPRVVDKELISPVLRKFWYGKYESV-------------------ASEEKNN--- 683
            .....|.|....||....:....|||...|..:..:                   ..|:..|
Zfish   484 LTRMVLEFAFPPPRCGVFDPAPSVLRSMHYLHFAIILCALTAIVVAVISLLTPPPTEEQTRNLTW 548

  Fly   684 FNLHES-ETQLKLEQ 697
            :.||.| |.::.|::
Zfish   549 WTLHNSTEREIPLQK 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	122/584 (21%)
slc5a10	XP_017211446.2	SLC5sbd_SGLT5	17..637	CDD:212058	137/662 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580124
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740