DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31089 and lipa

DIOPT Version :9

Sequence 1:	NP_733128.1	Gene:	CG31089 / 43135	FlyBaseID:	FBgn0051089	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_001015847.2	Gene:	lipa / 548564	XenbaseID:	XB-GENE-952977	Length:	409	Species:	Xenopus tropicalis

Alignment Length:	424	Identity:	149/424 - (35%)
Similarity:	214/424 - (50%)	Gaps:	45/424 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SLLVLVALAVGVYSA---AIDGPIDFYKLYD-NPEAHISLKSKITTADRTAAHGYPSEHHHIVTE 67
            :|:..|||...|.|.   .:.|.:    ||. :|||.:::...|      ...|||||.:.::||
Frog    14 ALIPAVALTDDVPSRIRHGVAGDL----LYSADPEATMNISELI------RYRGYPSEEYEVLTE 68

  Fly    68 DGYILGVFRIPYSHKLQNQNEKRPIVLLQHGLTSCSDAWILQGPNDGLPYLLADAGFDVWMGNAR 132
            |||||.|.|||:..|..::..| |:|.|||||.:....|:....|:.|.::|||||:|||:||:|
Frog    69 DGYILSVNRIPHGVKYASEGPK-PVVFLQHGLLADGSNWVTNLENNSLGFILADAGYDVWIGNSR 132

  Fly   133 GTSYSRNHTTLSPDHPNFWKFSWHEIGIYDITAIIDYALSTENGQGQDAIHYVGHSQGTTVFFAL 197
            |.::||.|.:||||...||.||:.|:...|:.|::|:....   .||:.|.|||||||||:.|..
Frog   133 GNTWSRKHKSLSPDQEEFWAFSYDELAKKDLPAVVDFITKK---TGQEQIFYVGHSQGTTIAFIA 194

  Fly   198 MSWIPEYNDKIKTAHMFAPVAIMKNLSSGLVRSVGPYLGHRNTYSV--LFGSQEFLPHNEFLM-- 258
            .|.:|:...|||.....||||.:|...|.|.:     ||....:.:  |||..||||....:.
Frog   195 FSSLPQLAKKIKMYFGLAPVATVKFSKSPLAK-----LGVLPEFLIEELFGKGEFLPQTYLITWL 254

  Fly   259 -------AIFFNICQPDFMLRPVCESAMEKLYAGGRVNMTAMPEGMATH-PAGCSTDQMLHYLQE 315
                   ||...:|...|.|   .....||.....|||:      .::| |||.|...|||:.|.
Frog   255 ATHFCTHAIADELCGNIFFL---LSGFNEKNLNMSRVNV------YSSHCPAGTSVQNMLHWRQG 310

  Fly   316 QQSGYFRLFDHGTKKNLEVYGTQEPPEYPVELINSLVHMWYADSDNLAAVEDVEQIAERLPNKVM 380
            .:||..:.||.|||.|:..|....||.|.|..:.....:|...:|.||..:||..:..::.|.|.
Frog   311 VRSGELKAFDFGTKGNMIHYNQTTPPFYHVRDMTVPTALWTGGNDWLADRKDVALLLTQVSNLVY 375

  Fly   381 HRMADTEWNHGDFALNWEVRKYINEPVIDIMMEY 414
            |:.. .:|.|.||....:..:.:...:|.:|.::
Frog   376 HKEI-PDWEHLDFIWGLDAPERMYNEIIAMMKKF 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31089	NP_733128.1	Abhydro_lipase	48..110	CDD:282003	26/61 (43%)
CG31089	NP_733128.1	Abhydrolase	<86..>237	CDD:304388	64/150 (43%)
lipa	NP_001015847.2	Abhydro_lipase	49..110	CDD:282003	27/67 (40%)
		PLN02872	50..409	CDD:215470	137/384 (36%)
		Abhydrolase_5	91..>229	CDD:289465	63/145 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2899
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.170