DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31089 and Lipf

DIOPT Version :9

Sequence 1:	NP_733128.1	Gene:	CG31089 / 43135	FlyBaseID:	FBgn0051089	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_059037.1	Gene:	Lipf / 50682	RGDID:	708441	Length:	395	Species:	Rattus norvegicus

Alignment Length:	424	Identity:	144/424 - (33%)
Similarity:	215/424 - (50%)	Gaps:	51/424 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LVLVALAVGVYSAAID-----GPIDFYKLYDNPEAHISLKSKITTADRTAAHGYPSEHHHIVTED 68
            |:|:...:..:..|..     ||       .||||::::...||      ..|||.:.:.:||||
  Rat     3 LLLITSVISTFGGAHGLFGKLGP-------GNPEANMNISQMIT------YWGYPCQEYEVVTED 54

  Fly    69 GYILGVFRIPYSHKLQNQNEKRPIVLLQHGLTSCSDAWILQGPNDGLPYLLADAGFDVWMGNARG 133
            ||||||:|||:.........|||:|.|||||.:.:..||...||:.|.::|||||:|||:||:||
  Rat    55 GYILGVYRIPHGKNNSENIGKRPVVYLQHGLIASATNWIANLPNNSLAFMLADAGYDVWLGNSRG 119

  Fly   134 TSYSRNHTTLSPDHPNFWKFSWHEIGIYDITAIIDYALSTENGQGQDAIHYVGHSQGTTVFFALM 198
            .::||.:...|||...||.||:.|:..||:.|.|::.:..   .||:.|||||||||||:.|...
  Rat   120 NTWSRKNVYYSPDSVEFWAFSFDEMAKYDLPATINFIVQK---TGQEKIHYVGHSQGTTIGFIAF 181

  Fly   199 SWIPEYNDKIKTAHMFAPVAIMKNLSSGL--VRSVGPYLGHRNTYSVLFGSQEFLPHNEFLMAIF 261
            |..|....||||.:..||||.:|...|.|  :..:..:|     :.::||.:.||||..|
  Rat   182 STNPTLAKKIKTFYALAPVATVKYTQSPLKKISFIPTFL-----FKLMFGKKMFLPHTYF----- 236

  Fly   262 FNICQPDFMLRPVCESAMEKLYAGG-----------RVNMTAMPEGMATHPAGCSTDQMLHYLQE 315
                 .||:...||...:..|....           .:|::.....:..:|||.|....||:.|.
  Rat   237 -----DDFLGTEVCSREVLDLLCSNTLFIFCGFDKKNLNVSRFDVYLGHNPAGTSVQDFLHWAQL 296

  Fly   316 QQSGYFRLFDHGT-KKNLEVYGTQEPPEYPVELINSLVHMWYADSDNLAAVEDVEQIAERLPNKV 379
            .:||.|:.|:.|: .:|:..|..:.||||.|..:...|.:|...:|.||..:||..:..:|.|.:
  Rat   297 VRSGKFQAFNWGSPSQNMLHYNQKTPPEYDVSAMTVPVAVWNGGNDILADPQDVAMLLPKLSNLL 361

  Fly   380 MHRMADTEWNHGDFALNWEVRKYINEPVIDIMME 413
            .|:.. ..:||.||....:..:.:...:|.:|.|
  Rat   362 FHKEI-LAYNHLDFIWAMDAPQEVYNEMISMMAE 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31089	NP_733128.1	Abhydro_lipase	48..110	CDD:282003	27/61 (44%)
CG31089	NP_733128.1	Abhydrolase	<86..>237	CDD:304388	68/152 (45%)
Lipf	NP_059037.1	PLN02872	4..389	CDD:215470	140/416 (34%)
		Abhydro_lipase	34..96	CDD:282003	29/67 (43%)
		Abhydrolase_5	77..>221	CDD:289465	66/151 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335432
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.000