DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31089 and lipf

DIOPT Version :9

Sequence 1:	NP_733128.1	Gene:	CG31089 / 43135	FlyBaseID:	FBgn0051089	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_998569.1	Gene:	lipf / 406713	ZFINID:	ZDB-GENE-040426-2737	Length:	396	Species:	Danio rerio

Alignment Length:	429	Identity:	142/429 - (33%)
Similarity:	215/429 - (50%)	Gaps:	63/429 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SLLVLVALAVGVYSAAIDGP-IDFYKLYDNPEAHISLKSKITTADRTAAH-GYPSEHHHIVTEDG 69
            ||::|.:..|....:|:||. :|       ||.::::...|       .| |||:|...:|||||
Zfish     7 SLVILTSGLVQYGQSALDGTGLD-------PEVNMNISEII-------RHWGYPAEEFEVVTEDG 57

  Fly    70 YILGVFRIPYSHKLQNQNEK-RPIVLLQHGLTSCSDAWILQGPNDGLPYLLADAGFDVWMGNARG 133
            |||.:.|||  |.::|:||: :|:|.|||||.:....|:...||:.|.::|||||||||:||:||
Zfish    58 YILSINRIP--HGVKNKNEEVKPVVFLQHGLLAAGSNWVTNLPNNSLGFVLADAGFDVWIGNSRG 120

  Fly   134 TSYSRNHTTLSPDHPNFWKFSWHEIGIYDITAIIDYALSTENGQGQDAIHYVGHSQGTTVFFALM 198
            .::|..|.:|.|....:||||..|:...|:.|:|::....   .||:.|.|||||||||:.|...
Zfish   121 NTWSCKHVSLDPRQKEYWKFSHDEMAKKDLPAVINFITKM---TGQEQIFYVGHSQGTTIAFMAF 182

  Fly   199 SWIPEYNDKIKTAHMFAPVAIMKNLSSGLVRSVGPYLGHRNTYSV--LFGSQEFLPHNEFLM--- 258
            |.:||...|||.....||||.:     |:.:|....|.....:.:  |||.::|.|.||.:.
Zfish   183 STMPELASKIKMFFALAPVATV-----GMTKSPMTKLSVIPEFLIWDLFGQKDFFPQNELIKFFA 242

  Fly   259 --------------AIFFNICQPDFMLRPVCESAMEKLYAGGRVNMTAMPEGMATHPAGCSTDQM 309
                          .:||.:|..|           ||     .:||:..|...|..|||.|...|
Zfish   243 TEFCSRKPLSVLCGNVFFLLCGFD-----------EK-----NLNMSRTPVYTAHCPAGTSVQNM 291

  Fly   310 LHYLQEQQSGYFRLFDHGTKKNLEVYGTQEPPEYPVELINSLVHMWYADSDNLAAVEDVEQIAER 374
            :|:.|..:|.....:|:|...|:..|....||.|.::.:.....:|....|.||..:||..:..:
Zfish   292 IHWAQAVKSSKLMAYDYGRAGNMAHYNQSTPPLYNIQDMMVPTAVWSGGQDTLADPKDVALLLTQ 356

  Fly   375 LPNKVMHRMADTEWNHGDFALNWEVRKYINEPVIDIMME 413
            :| |::::.....|.|.||....:..:.:.|.:|:||.|
Zfish   357 IP-KLVYKRDIKHWEHLDFIWGMDAPQEMYEKMIEIMRE 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31089	NP_733128.1	Abhydro_lipase	48..110	CDD:282003	28/63 (44%)
CG31089	NP_733128.1	Abhydrolase	<86..>237	CDD:304388	64/151 (42%)
lipf	NP_998569.1	PLN02872	4..393	CDD:215470	140/426 (33%)
		Abhydro_lipase	36..97	CDD:282003	29/69 (42%)
		Abhydrolase_5	78..242	CDD:289465	69/171 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574731
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.950