DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31089 and Lipm

DIOPT Version :9

Sequence 1:	NP_733128.1	Gene:	CG31089 / 43135	FlyBaseID:	FBgn0051089	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	XP_220066.4	Gene:	Lipm / 309528	RGDID:	1304912	Length:	422	Species:	Rattus norvegicus

Alignment Length:	425	Identity:	150/425 - (35%)
Similarity:	208/425 - (48%)	Gaps:	53/425 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLVLVALAVGVYSAAIDGPIDFYKLYDN------------PEAHISLKSKITTADRTAAH-GYPS 59
            ||:|||                |.|..|            |||.:::...|       .| ||||
  Rat    19 LLILVA----------------YLLQRNVNSGHMPTKAADPEAFMNVSEII-------KHKGYPS 60

  Fly    60 EHHHIVTEDGYILGVFRIPYSHKLQNQNEKRPIVLLQHGLTSCSDAWILQGPNDGLPYLLADAGF 124
            |.:.:.|||||||.|.|||.......:...||:|||||||...:..||...||:.|.::||||||
  Rat    61 EEYEVATEDGYILSVNRIPRGQTQLKKEGSRPVVLLQHGLLGDASNWISNLPNNSLGFILADAGF 125

  Fly   125 DVWMGNARGTSYSRNHTTLSPDHPNFWKFSWHEIGIYDITAIIDYALSTENGQGQDAIHYVGHSQ 189
            ||||||:||.::||.|.|||.|...||.||:.|:..:|:.|:|::.|..   .||..|:|||:||
  Rat   126 DVWMGNSRGNTWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQK---TGQKKIYYVGYSQ 187

  Fly   190 GTTVFFALMSWIPEYNDKIKTAHMFAPVAIMKNLSS-GLVRSVGPYLGHRNTYSVLFGSQEFLPH 253
            |||:.|...|.:||...|||.....||:|.:|:..| |....:.|.:..:.    |||.||||..
  Rat   188 GTTMGFIAFSTMPELAHKIKMYFALAPIATVKHAKSPGTKFLLLPDMMIKG----LFGRQEFLYQ 248

  Fly   254 NEFLMAIFFNICQPDFMLRPVCESAMEKLYAGG----RVNMTAMPEGMATHPAGCSTDQMLHYLQ 314
            ..|...:|..:| ...:|..:|.:.:  |..||    .:||:.....:|..|||.|...:||:.|
  Rat   249 TRFFRQLFIYLC-GQMILDQICSNII--LLLGGFNTNNMNMSRANVYVAHTPAGTSVQNILHWSQ 310

  Fly   315 EQQSGYFRLFDHGTK-KNLEVYGTQEPPEYPVELINSLVHMWYADSDNLAAVEDVEQIAERLPNK 378
            ...||..|.||.|:: ||.|......|..|.|..:.....||....|.|:..:||:.:...:.|.
  Rat   311 AVNSGELRAFDWGSETKNREKSNQPTPIRYKVRDMMVPTAMWTGGQDWLSNPDDVKTLLSEVTNL 375

  Fly   379 VMHRMADTEWNHGDFALNWEVRKYINEPVIDIMME 413
            :.|:.. .||.|.||....:....:...:|.:|.:
  Rat   376 IYHKNI-PEWAHVDFIWGLDAPHRVYNEIIHLMKQ 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31089	NP_733128.1	Abhydro_lipase	48..110	CDD:282003	28/62 (45%)
CG31089	NP_733128.1	Abhydrolase	<86..>237	CDD:304388	69/151 (46%)
Lipm	XP_220066.4	Abhydro_lipase	49..111	CDD:282003	29/68 (43%)
		Abhydrolase_1	92..392	CDD:278959	118/310 (38%)
		Abhydrolase_5	93..>231	CDD:289465	66/140 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335454
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.000