DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31089 and Lipo1

DIOPT Version :9

Sequence 1:	NP_733128.1	Gene:	CG31089 / 43135	FlyBaseID:	FBgn0051089	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	XP_006231364.1	Gene:	Lipo1 / 294097	RGDID:	1565682	Length:	397	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	123/392 - (31%)
Similarity:	208/392 - (53%)	Gaps:	34/392 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 NPEAHISLKSKITTADRTAAHGYPSEHHHIVTEDGYILGVFRIPYSHKLQNQNEKRPIVLLQHGL 99
            |||:|:::...|      ....|||..:.:||:|||||.:.|||:.....|.:..:.:|..||||
  Rat    26 NPESHMNVSEII------KYWNYPSLEYEVVTDDGYILPINRIPHGKNNANSSAPKMVVFCQHGL 84

  Fly   100 TSCSDAWILQGPNDGLPYLLADAGFDVWMGNARGTSYSRNHTTLSPDHPNFWKFSWHEIGIYDIT 164
            .|....|:...|::.|.::||:||:|||:||:||:::::.|.|||||...||.||:.::..||:.
  Rat    85 FSTPGVWVANPPDNSLAFILAEAGYDVWLGNSRGSTWAKKHVTLSPDSEEFWAFSFDQMIAYDLP 149

  Fly   165 AIIDYALSTENGQGQDAIHYVGHSQGTTVFFALMSWIPEYNDKIKTAHMFAPVAIMKNLSSGLVR 229
            |.|::.|:|   .||:.|:|:|||.||.:.....|...|..:|||...:.|||..:|     .|:
  Rat   150 ATINFILNT---TGQEQIYYIGHSLGTLIALGAFSTNQELAEKIKLNILIAPVRTVK-----YVK 206

  Fly   230 SVGPYLGH--RNTYSVLFGSQEFLPHNEFLMAIFFN-----ICQPDFMLRPVCESAMEKL--YAG 285
            ..|..|.:  ...:.::||.:||||      .:.|:     :|... ::...|...:..|  ::.
  Rat   207 GFGRLLAYFSPEAFKLVFGKKEFLP------TVVFSEYSKYVCNIK-LVDAGCAGVLGSLTGFSE 264

  Fly   286 GRVNMTAMPEGMATHP-AGCSTDQMLHYLQEQQSGYFRLFDHGTKK-NLEVYGTQEPPEYPVELI 348
            .::| |:..:...||. ||.||..::|..|..:||.|:.:|.|:.. |::.|....||.|.||.:
  Rat   265 DQLN-TSRIDVYITHSLAGTSTQILIHAGQAIRSGEFQAYDWGSPSLNMQHYNQTTPPLYSVENM 328

  Fly   349 NSLVHMWYADSDNLAAVEDVEQIAERLPNKVMHRMADTEWNHGDFALNWEVRKYINEPVIDIMME 413
            .....|:....|.||..:||..:..::.|.:.|:.. .|::|.||.:....:..:::.::.|:.|
  Rat   329 KVPTVMFTGLKDFLADPKDVANLVPKIFNLIYHKTI-PEFSHLDFIVGLNAKTEVSDEILTILGE 392

  Fly   414 YE 415
            |:
  Rat   393 YD 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31089	NP_733128.1	Abhydro_lipase	48..110	CDD:282003	21/61 (34%)
CG31089	NP_733128.1	Abhydrolase	<86..>237	CDD:304388	57/150 (38%)
Lipo1	XP_006231364.1	Abhydro_lipase	33..94	CDD:282003	22/66 (33%)
		Abhydrolase_1	77..375	CDD:278959	101/314 (32%)
		Abhydrolase_5	77..>199	CDD:289465	51/124 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335477
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.000