DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31089 and SPBC16A3.12c

DIOPT Version :9

Sequence 1:	NP_733128.1	Gene:	CG31089 / 43135	FlyBaseID:	FBgn0051089	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_596777.1	Gene:	SPBC16A3.12c / 2539875	PomBaseID:	SPBC16A3.12c	Length:	443	Species:	Schizosaccharomyces pombe

Alignment Length:	446	Identity:	123/446 - (27%)
Similarity:	206/446 - (46%)	Gaps:	58/446 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FTGSLLVLVALAVGVYSAAIDGPIDFYKLYDNPEA-------------HISLKSKITTADRTA-- 53
            :.|..:.::|..||||:..: ..|..|.:   ||.             |..:.||.|.....|
pombe    10 YWGDYVGVIAAFVGVYTELV-ARIFIYMI---PERVREWFRVRIIVLYHYYISSKTTDGMTDAVQ 70

  Fly    54 ----------AHGYPSEHHHIVTEDGYILGVFRIPYSHKLQNQNEKRPIVLLQHGLTSCSDAWIL 108
                      |.||..|.|.:.|:|.:||.:.||  :|..|:|: ||.:|...|||.:.|:.|:.
pombe    71 KCRNIYEICEAFGYRVEEHLVRTQDNFILCLHRI--THPKQSQH-KREVVYCHHGLMTNSELWVA 132

  Fly   109 QGPND-GLPYLLADAGFDVWMGNARGTSYSRNHTTLSPDHPNFWKFSWHEIGIYDITAIIDYALS 172
            ...:: .||::|.::|:|||:||.||..|||.|.|..|....||.||..::.::||...:||.|
pombe   133 VNESERSLPFVLIESGYDVWLGNNRGNKYSRKHITYKPKDEEFWNFSLDDMAMFDIPDTVDYIL- 196

  Fly   173 TENGQGQDAIHYVGHSQGTTVFFALMSWIPEYNDKIKTAHMFAPVAIMKNLSSGLVR---SVGPY 234
              ...|::.::|:|.||||....|.:|..|:.|||:......||....|..|:..|.   .|.|.
pombe   197 --RETGREKLNYIGFSQGTAQAMAALSINPDLNDKVNIFIGLAPAYAPKGFSNYFVDYIVKVNPK 259

  Fly   235 LGHRNTYSVLFGSQEFLPHNEFLMAIFFNICQPDFMLRPVCESAMEKLYAGGRVNMTAMPE--GM 297
            :.:.     |||.:..||...|    :.|||.|...:: :.:.:::.|:.....|::...:  |.
pombe   260 IMYH-----LFGRRCLLPSVTF----WQNICYPPIFVK-IVDVSLKILFNWDLSNISLNQKLCGY 314

  Fly   298 ATHPAGCSTDQMLHYLQEQQSGYFRLFDHGTKKNLEVYGTQ--EPPEYPVELINSLVHMWYADSD 360
            |...:..|...::|:||..::..|:|:|..... |..||::  :.|.:|...|...:.:.:...|
pombe   315 AHLYSFSSVKSVVHWLQIIKNCTFQLYDDDMAL-LAGYGSRHYQVPLFPTNNIKCPMLILWGGKD 378

  Fly   361 NLAAVEDVEQIAERLPNKVMHRMADTEWNHGDFALNWEVRKYINEPVIDIMMEYEL 416
            .|.   ::|.:...||... ..::...:.|.||....:|::.:...|||.:..:.|
pombe   379 TLI---NMEVMRTALPPHA-KEVSIAHYEHLDFLWGQDVKEEVFPVVIDALKHHSL 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31089	NP_733128.1	Abhydro_lipase	48..110	CDD:282003	23/73 (32%)
CG31089	NP_733128.1	Abhydrolase	<86..>237	CDD:304388	55/154 (36%)
SPBC16A3.12c	NP_596777.1	Abhydro_lipase	75..131	CDD:282003	21/58 (36%)
		Abhydrolase_1	116..410	CDD:278959	87/311 (28%)
		Abhydrolase	<171..>242	CDD:304388	24/73 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1506
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	9	8.990