Protein Alignment Mco3 and cueO

DIOPT Version :10

• Sequence 1: NP_651441.1
• Gene: Mco3 / 43134
• FlyBaseID: FBgn0039387
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_414665.1
• Gene: cueO / 947736
• ECOCYCID: EG12318
• Length: 516
• Species: Escherichia coli
• Alignment Length: 529
• Identity: 124/529 - (23%)
• Similarity: 204/529 - (38%)
• Gaps: 127/529 - (24%)

  Fly   164 GPSIELCENDTVVVDVLNYLSEPTTMHWHGVHMHRTPEMDGAPFITQYPLQPGEVQRHEFKVDR- 227
            ||:::|.....|.||:.|.|:|.||:||||:.:  ..|:||.|   |..:.||..:.....||:
E. coli    75 GPAVKLQRGKAVTVDIYNQLTEETTLHWHGLEV--PGEVDGGP---QGIIPPGGKRSVTLNVDQP 134

  Fly   228 SGSLWYHSH----VGWQRGFGVAGAFVVRQTSQENQHSQLY---DYDLVEHTLMIQDIFY----- 280
            :.:.|:|.|    .|.|...|:||..|:    ::::..:|.   .:.:.:..:::||..:
E. coli   135 AATCWFHPHQHGKTGRQVAMGLAGLVVI----EDDEILKLMLPKQWGIDDVPVIVQDKKFSADGQ 195

  Fly   281 -EYNLQDVRNILVNGKGRNHLSQ---LPDNDNRHRYERLRVTPGYRYRMRVILNGIANCPVEFSI 341
             :|.| ||....|...|...|:.   .|.:.....:.|||           :|||.....:.|:.
E. coli   196 IDYQL-DVMTAAVGWFGDTLLTNGAIYPQHAAPRGWLRLR-----------LLNGCNARSLNFAT 248

  Fly   342 EQHR-LLMISTDGNDI-EPVLADGFFLTSAERFDFVLEANQYK---------KNYWIRIKGYEQC 395
            ..:| |.:|::||..: |||......:...|||:.::|.|..|         ....:.|..:::.
E. coli   249 SDNRPLYVIASDGGLLPEPVKVSELPVLMGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKP 313

  Fly   396 ENRNIYQGAVLSYRGSARSELPQGDILDKPSSRAADEDL--ILVNDFRFKPANSTAISSLRQSLD 458
            ......|...:|..|:    ||     |..||..|...|  :.|...:........:..::..::
E. coli   314 HPVMRIQPIAISASGA----LP-----DTLSSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLME 369

  Fly   459 KDNNVGTVALRSVDPVPWTRYTKFLTHYSSFGSRTAPN--GEVLFQISDISYNSPGISLLQGRHL 521
            |   .|..|:..:|      :::.:.| ...|:....|  |:..|..:: ..|.....:
E. coli   370 K---YGDQAMAGMD------HSQMMGH-MGHGNMNHMNHGGKFDFHHAN-KINGQAFDM------ 417

  Fly   522 YQDDRYFCNKSSLAAEGRNCERELCECVNVMRLPAYRPLEMVVANYLDSTHPFHIHGFTFRLVGQ 586
                    ||...||.....||.:...|..|.|                 |||||||..||:
E. coli   418 --------NKPMFAAAKGQYERWVISGVGDMML-----------------HPFHIHGTQFRI--- 454

  Fly   587 GVLGNLNDLRNIQELDRRGRLPRLSEDSAAVAKDTVQIPGQ-GYIIVRFISNNPGFWLY--HCHV 648
                          |...|:.|....   |..||||::.|. ..::|:|..:.|....|  |||:
E. coli   455 --------------LSENGKPPAAHR---AGWKDTVKVEGNVSEVLVKFNHDAPKEHAYMAHCHL 502

  Fly   649 EAHAVQGMV 657
            ..|...||:
E. coli   503 LEHEDTGMM 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mco3	NP_651441.1	CuRO_1_tcLCC2_insect_like	149..252	CDD:259927	33/92 (36%)
		laccase	151..656	CDD:274556	122/526 (23%)
		CuRO_2_tcLCC_insect_like	270..408	CDD:259951	33/157 (21%)
cueO	NP_414665.1	PRK10965	1..516	CDD:236810	124/529 (23%)