Protein Alignment Mco3 and FET3

DIOPT Version :10

• Sequence 1: NP_651441.1
• Gene: Mco3 / 43134
• FlyBaseID: FBgn0039387
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_013774.1
• Gene: FET3 / 855080
• SGDID: S000004662
• Length: 636
• Species: Saccharomyces cerevisiae
• Alignment Length: 552
• Identity: 137/552 - (24%)
• Similarity: 231/552 - (41%)
• Gaps: 106/552 - (19%)

  Fly   149 DGV-ANPVMAVNRMVPGPSIELCENDTVVVDVLNYLSEP-TTMHWHGVHMHRTPEMDGAPFITQY 211
            ||: :.||:..|...|.|.|.:.:.|.|.:.:.|.::.. |:||:||:..:.|..|||.||:||.
Yeast    38 DGLKSRPVITCNGQFPWPDITVNKGDRVQIYLTNGMNNTNTSMHFHGLFQNGTASMDGVPFLTQC 102

  Fly   212 PLQPGEVQRHEFKVDRS-GSLWYHSHVGWQRGFGVAGAFVVRQTSQENQHSQLYDYDLVEHTLMI 275
            |:.||....:.|.||.: |:.|||||...|...|:.|.|:::..|..      |||| .|.:|.:
Yeast   103 PIAPGSTMLYNFTVDYNVGTYWYHSHTDGQYEDGMKGLFIIKDDSFP------YDYD-EELSLSL 160

  Fly   276 QDIFYEYNLQDVRNIL--VNGKGRNHLSQ--LPDNDNRHRYERLRVTPGYRYRMRVI-LNGIANC 335
            .:.:::......::.:  .|..|...:.|  :.:|.....:|   |.|...|.:|:: :.|..:
Yeast   161 SEWYHDLVTDLTKSFMSVYNPTGAEPIPQNLIVNNTMNLTWE---VQPDTTYLLRIVNVGGFVS- 221

  Fly   336 PVEFSIEQHRLLMISTDGNDIEPVLADGFFLTSAERFDFVLEA-NQYKKNYWIRIKGYEQCENRN 399
             ..|.||.|.:.::..||...|..:.|..::|.|:|:..::.. |...||:.|..|
Yeast   222 -QYFWIEDHEMTVVEIDGITTEKNVTDMLYITVAQRYTVLVHTKNDTDKNFAIMQK--------- 276

  Fly   400 IYQGAVLSYRGS-----ARSELPQGDILDKPSSRAADEDLILVNDFRFKPANSTAISSLRQSLDK 459
             :...:|....|     |.|.:........|:....|.....::||..:|....||..     :.
Yeast   277 -FDDTMLDVIPSDLQLNATSYMVYNKTAALPTQNYVDSIDNFLDDFYLQPYEKEAIYG-----EP 335

  Fly   460 DNNVGTVALRSVDPVPWTRYTKFLTHYSSFGSRTAPNGEVLFQISDISYNSPGISLLQGRHLYQD 524
            |:.:      :||.|                .....||......::|:|.:|.:..|. ..|...
Yeast   336 DHVI------TVDVV----------------MDNLKNGVNYAFFNNITYTAPKVPTLM-TVLSSG 377

  Fly   525 DRYFCNKSSLAAEGRNCERELCECVNVMRLPAYRPLEMVVANYLDSTHPFHIHGFTFRLVGQGVL 589
            |:  .|.|.:  .|.|....:.|...:        :|:|:.|....|||||:||..|:.:
Yeast   378 DQ--ANNSEI--YGSNTHTFILEKDEI--------VEIVLNNQDTGTHPFHLHGHAFQTI----- 425

  Fly   590 GNLNDLRNIQELDRRGRLPRLSEDSAAVA-------KDTVQIPGQGYIIVRFISNNPGFWLYHCH 647
                 .|:....|..|.:|...:.....|       :||:.:..|...::||.::|||.|.:|||
Yeast   426 -----QRDRTYDDALGEVPHSFDPDNHPAFPEYPMRRDTLYVRPQSNFVIRFKADNPGVWFFHCH 485

  Fly   648 VEAHAVQGMVAVL-------------KIGEDH 666
            :|.|.:||:..||             ::.|:|
Yeast   486 IEWHLLQGLGLVLVEDPFGIQDAHSQQLSENH 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mco3	NP_651441.1	CuRO_1_tcLCC2_insect_like	149..252	CDD:259927	40/105 (38%)
		laccase	151..656	CDD:274556	130/525 (25%)
		CuRO_2_tcLCC_insect_like	270..408	CDD:259951	29/143 (20%)
FET3	NP_013774.1	CuRO_1_Fet3p	24..144	CDD:259920	40/105 (38%)
		CuRO_2_Fet3p_like	154..301	CDD:259945	32/161 (20%)
		CuRO_3_Fet3p	336..489	CDD:259966	46/197 (23%)