Protein Alignment Mco3 and LOC5668122

DIOPT Version :10

• Sequence 1: NP_651441.1
• Gene: Mco3 / 43134
• FlyBaseID: FBgn0039387
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_001688594.2
• Gene: LOC5668122 / 5668122
• VectorBaseID: AGAMI1_002328
• Length: 698
• Species: Anopheles gambiae
• Alignment Length: 704
• Identity: 218/704 - (30%)
• Similarity: 314/704 - (44%)
• Gaps: 150/704 - (21%)

  Fly    56 FPQAKFEWPSFAWMRNKTTKGTPALD----LKNDYSQMELANFGDFDRHPCRRVCQQGQSQN-CY 115
            :|:|.|  ||.    .|...|...||    .|:....:.||.|  .|...|.|:|.:.::.. ||
Mosquito    41 YPKAVF--PSV----GKFMAGPQFLDAVRSAKDRPVPLHLAEF--HDGAECDRICTEREAPRVCY 97

  Fly   116 YQLVVHNYQRLGPECQRCQFDERA-CASEHCIYGDGVANPVMAVNRMVPGPSIELCENDTVVVDV 179
            ::.:..:|..:|..|..|::..|: |....||..||:...|:|:||.:|||:|.:|.:|.:||||
Mosquito    98 FRWIAEHYAAMGSACGDCRWGNRSHCFHPQCITADGMERGVLALNRRIPGPTIHVCRHDLIVVDV 162

  Fly   180 LNYLSE-PTTMHWHGVHMHRTPEMDGAPFITQYPLQPGEVQRHEFKVDRSGSLWYHSHVGWQRGF 243
            :|::.. .:|:||||.|.:.||.|||.|.|||.|:..|...|:.|.....|:..||||.|.|:..
Mosquito   163 VNHMEGLESTIHWHGAHQYDTPWMDGVPMITQCPIPNGAAFRYAFNASEPGTQLYHSHSGHQKAN 227

  Fly   244 GVAGAFVVRQTSQENQHSQLYDYDLVEHTLMIQDIFYEY------NLQD--VR--NILVNGKGRN 298
            |..|.||:|..:..|.|  ||||||.||.::|.|...:.      .||.  ||  :||:||:||:
Mosquito   228 GHYGLFVIRSPTDINHH--LYDYDLTEHHIIISDWTLDLVEKFVPGLQSSTVRMDSILINGRGRH 290

  Fly   299 HLSQLPDNDNRHRYER------LRVTPGYRYRMRVILNGIANCPVEFSIEQHRLLMISTDGNDIE 357
            .      ::..|..:.      .||..|||||.|::.:|...||.:..||:||:.:|:|||..::
Mosquito   291 F------DEEEHELQTQAPLTVYRVKKGYRYRFRLVSSGSQFCPFQLQIEKHRMQLIATDGGAVQ 349

  Fly   358 PVLADGFFLTSAERFDFVLEANQYKKNYWIRIKGYEQCENRNIYQGAVLSYRGSAR--------- 413
            |.:.|....||.||:||||.|||....||:|::....|......:.|||||...|.
Mosquito   350 PTMVDTLISTSGERYDFVLSANQKPGTYWVRVRAIGFCNIERREEFAVLSYEDEAHPVQEEVLAY 414

  Fly   414 ---------SELPQGDILDKPSSRA---ADEDL--------------------------ILVNDF 440
                     ...|.|.:|:.|::..   .|:||                          ||.|.|
Mosquito   415 PKRTPPSWDDRFPSGTVLNNPNATCYVPGDDDLCVADLESHEVHRDDDLIDAAPNKTFRILFNTF 479

  Fly   441 RFKPA----------NSTAISSLRQSLDKDNNVGTVALRSVDPVPWTRYTKFLTHYSSFGSRTAP 495
            ...||          ..|.:.:|       ||:|..
Mosquito   480 TADPAVLFSDQGYVRYMTVVLTL-------NNIGVT----------------------------- 508

  Fly   496 NGEVLFQISDISYNSPGISLLQGRHLYQDDRYFCNKSSLAAEGRNCE-RELCECVNVMRLPAYRP 559
                    ::||...|...||....|...|..|||.:...|   .|: ...|.|::.:::.....
Mosquito   509 --------NNISMVFPDFPLLTQPELIGGDGMFCNNTHRPA---RCKPHHACFCLHRLKVALNDV 562

  Fly   560 LEMVVAN----YLDSTHPFHIHGFTFRLVGQGVLGNL-NDLRNIQELDRRGRLPR-LSEDSAAVA 618
            :||.:.:    ..|..||||:||..|.:.|.|.|... .....:..::|..|..| :..|.....
Mosquito   563 VEMSLIDDAEVVRDLYHPFHLHGHRFIVTGMGQLPQFGTQSEKVDFVERARRYSRTMPSDHNPPY 627

  Fly   619 KDTVQIPGQGYIIVRFISNNPGFWLYHCHVEAHAVQGMVAVLKIGEDHQMKNIP 672
            ||||.:|.:||..:||.::||||||.|||.|.|...||..||::||..:||..|
Mosquito   628 KDTVSVPSRGYTRIRFRADNPGFWLVHCHFEWHLGIGMSFVLQVGELDEMKQAP 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mco3	NP_651441.1	CuRO_1_tcLCC2_insect_like	149..252	CDD:259927	47/103 (46%)
		laccase	151..656	CDD:274556	180/585 (31%)
		CuRO_2_tcLCC_insect_like	270..408	CDD:259951	54/153 (35%)
LOC5668122	XP_001688594.2	None