Protein Alignment Mco3 and hephl1a

DIOPT Version :10

• Sequence 1: NP_651441.1
• Gene: Mco3 / 43134
• FlyBaseID: FBgn0039387
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001314994.1
• Gene: hephl1a / 561607
• ZFINID: ZDB-GENE-070801-4
• Length: 1094
• Species: Danio rerio
• Alignment Length: 717
• Identity: 140/717 - (19%)
• Similarity: 222/717 - (30%)
• Gaps: 238/717 - (33%)

  Fly   125 RLGPECQRCQF----DERACASEHCIYGD---GVANPVMAVNRMVPGPSIELCENDTVVVDVLNY 182
            :||.:..:.::    |:...:..|.:..|   |:..||:...           ..|.::|..||.
Zfish   422 KLGGKYMKARYVQYTDQTFTSKTHIVGSDEHLGILGPVIRAE-----------TGDVIIVTFLNK 475

  Fly   183 LSEPTTMHWHGVHMHRTPE----MDGAPFITQYPLQPGEVQRHEFKV------------------ 225
            .....::..||:|..:..|    .||:   .:.|:.||:...:.::|
Zfish   476 ARRNYSIQPHGLHYEKVYEGAMYADGS---QKAPVGPGQKFTYRWRVIEGPSADDPPCISYLYYS 537

  Fly   226 ------------------------DRSGSLWYHSHV------------------GW--QRGFGVA 246
                                    ||||    |.|.                  .|  :....:.
Zfish   538 AVDPVRDTNSGLFGPIQVCKKGVLDRSG----HQHAEKIQHEFFLLFSVMDENESWYLEDNIAMF 598

  Fly   247 GAFVVRQTSQENQHS------------QLYDYDL------VEHT------LMIQDIFYEYNLQDV 287
            |:..|.....|.|.|            .|...||      |.||      |.|..|:::.|:
Zfish   599 GSPDVDPDKDEFQESNKMHAVNGFMYGNLPGLDLCNGEHVVWHTLGLGTELDIHGIYFQGNM--- 660

  Fly   288 RNILVNGKGRNHLSQLPDNDNRHRYERLRVTPGYRYRMRVILNGI--ANCPV----EFSIEQHRL 346
              ...||..|:.||..|     |....:.:||..        ||:  .:|..    ...:.||
Zfish   661 --FQRNGMNRDTLSIFP-----HTSVTVNMTPDN--------NGMFEVSCQTADHFHAGMRQH-- 708

  Fly   347 LMISTDGNDIEPVLAD---GFFLTSAERFDFVLEAN--QYKKNYWIRIKGYEQCENRNIYQGAVL 406
                   ..::|..|.   ....||..::....|..  .|..|....::.::..:..:|  |:|.
Zfish   709 -------YTVKPCSAKTPAPELFTSTRKYYIAAEEIIWNYAPNRTWELEKHKATQMESI--GSVY 764

  Fly   407 SYRGSAR--SELPQ-------GDILDKPSSRAADEDLILVNDFRFKPANSTAISSLRQSLDKDNN 462
            ..|...|  :|..:       .:...|...|.|||:.:.:    ..|.....:....:.:.|:|.
Zfish   765 LQRSKNRIGAEYKKVVYREYSDETFTKQKPRGADEEHLGI----MGPIIKGEVGEKIEVVFKNNA 825

  Fly   463 VGTVAL------------RSVDPVPWTRYTKFLTHYSSFGSRTAPNGEVLFQISDISYNSPGISL 515
            ....::            :.|.|....:||..:...|..|.:. |:.......|..|.....:|.
Zfish   826 SRPYSIHAHGVKTSEPHQKDVQPGNVLKYTWTIPKRSGPGPKD-PDCITFAYYSSTSLVKDLMSG 889

  Fly   516 LQGRHLYQDDRYFCNKSSLAAE----GRNCERELCECVNVMRLPAYRPLEMVVANYLD-STHPF- 574
            |.|..:      .|.|::|.|:    .||.|..|...|.......|  |:..:..||| ....|
Zfish   890 LVGPLI------VCRKNTLDADRQRKDRNKEFALLFMVFDENESHY--LDENIQQYLDVDLEEFD 946

  Fly   575 ----------HIHGFTFRLVGQGVLGNLNDLRNIQELDR-RGRLPRLSEDSAAVAKDTVQIPGQG 628
                      .:||...:|     ..||..| |:.|.|. :..|..|..:   |...||....|.
Zfish   947 KYAGDFMESNKMHGINGKL-----YSNLQGL-NMTEGDHTKWYLLGLGNE---VDMHTVHFHAQS 1002

  Fly   629 YI--------------------IVRFISNNPGFWLYHCHVEAHAVQGMVAVLKI---GEDHQMKN 670
            :|                    .:..|:.|||.||.||||..|...||.|:|.:   |.....:|
Zfish  1003 FIYKTDHFHRADVFDLFPGTFQTIELIAGNPGQWLLHCHVTDHIHAGMEALLTVNAKGSVSTRRN 1067

  Fly   671 IP 672
            .|
Zfish  1068 AP 1069

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mco3	NP_651441.1	CuRO_1_tcLCC2_insect_like	149..252	CDD:259927	26/171 (15%)
		laccase	151..656	CDD:274556	127/663 (19%)
		CuRO_2_tcLCC_insect_like	270..408	CDD:259951	30/154 (19%)
hephl1a	NP_001314994.1	CuRO_1_ceruloplasmin	23..205	CDD:259884
		Cupredoxin	218..362	CDD:473140
		CuRO_3_ceruloplasmin	376..567	CDD:259886	26/162 (16%)
		Cupredoxin	574..714	CDD:473140	30/166 (18%)
		Cupredoxin	728..899	CDD:473140	30/183 (16%)
		Cupredoxin	913..1056	CDD:473140	40/153 (26%)