Protein Alignment Mco3 and Mco1

DIOPT Version :10

• Sequence 1: NP_651441.1
• Gene: Mco3 / 43134
• FlyBaseID: FBgn0039387
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_609287.3
• Gene: Mco1 / 34258
• FlyBaseID: FBgn0032116
• Length: 959
• Species: Drosophila melanogaster
• Alignment Length: 747
• Identity: 245/747 - (32%)
• Similarity: 352/747 - (47%)
• Gaps: 141/747 - (18%)

  Fly    37 IVLLIFASNPSQCESSKDDFPQAKFEWPSFAWMRNKTTKGTPALDLKNDYSQMELANFGD----- 96
            ||:..:..|   |.:..:|.|.::.|      .||......|....:.:..|..:|...|
  Fly   182 IVMNTYKRN---CPALTEDCPASRLE------ERNCCPYCRPLQTARIEELQDNVAESTDDIWTA 237

  Fly    97 --FDRHPCRRVCQQG-QSQNCYYQLVVHNYQRLGPECQRCQFDERACASEHCIYGDGVANPVMAV 158
              :..|||.|.||.| :...|.|:.||..||.....|..|..:...|:..||:.|||:...:..|
  Fly   238 EWYRNHPCNRDCQVGAEPMTCRYKFVVEWYQTFSKACYDCPRNLTDCSRPHCVMGDGLERSITVV 302

  Fly   159 NRMVPGPSIELCENDTVVVDVLNY-LSEPTTMHWHGVHMHRTPEMDGAPFITQYPLQPGEVQRHE 222
            |||:|||:||:||.|.:||||.|: |.|.|::||||:|..:||.|||.|.|||.|:.|....|:.
  Fly   303 NRMMPGPAIEVCEGDEIVVDVKNHLLGESTSIHWHGLHQKKTPYMDGVPHITQCPITPHATFRYS 367

  Fly   223 FKVDRSGSLWYHSHVGWQRGFGVAGAFVVRQTSQENQHSQLYDYDLVEHTLMIQD---------- 277
            |..|.||:.::|||.|.|||.||.||.::|:......|..|||:||.||.:::||
  Fly   368 FPADLSGTHFWHSHTGMQRGDGVFGALIIRKPKTAEPHGGLYDFDLSEHVMIVQDWIHDTGASIF 432

  Fly   278 IFYEYNLQDVR--NILVNGKGR------------------------------------------- 297
            .::.::..|.:  |:|||||||
  Fly   433 SYHHHSRGDNKPHNLLVNGKGRYYNRIWAEAKQAHRRAEERTTQPVEPLPKSQVDFVQTLPRQAR 497

  Fly   298 ----NHLSQLPDNDNRHR------------YERLRVTPGYRYRMRVILNGIANCPVEFSIEQHRL 346
                |.....|.|..:.|            ::...|..|:|||.|:|.....|||:..||:.|.|
  Fly   498 LAKTNTTKLFPVNSRQKRGNLNEIPLELVPHQIYTVRRGFRYRFRIINAEYLNCPIVVSIDGHNL 562

  Fly   347 LMISTDGNDIEPVLADGFFLTSAERFDFVLEANQYKKNYWIRIKGYEQCEN--RNIYQGAVLSYR 409
            ..|::||.|||.:........|.|||||||.||....|||||:||...|..  .:.:|.|:|.|.
  Fly   563 TAINSDGFDIEAMDVGSIVTYSGERFDFVLNANLEVGNYWIRLKGLMDCSEVFTSAFQVAILRYE 627

  Fly   410 GSARSELPQGDILDKPSSRAADEDLILVNDFRFKPANSTAISSLRQSLDKDNNVGTVALRSVDPV 474
            | |..|.|..::  ....:|...:|.::|.....|...| ::.:|            ||...|.|
  Fly   628 G-APDEEPTAEL--SYGHKAEGIELNVMNRGPGYPDTKT-VAEMR------------ALPIYDHV 676

  Fly   475 ---------PWTRYTKFLTHYSSFGSR----------------TAPNGEVLFQISDISYNSPGIS 514
                     |...| ||..:|..:...                |..|.....|::.|:.|.|.::
  Fly   677 SGIDHDTLKPEADY-KFFIYYDFYTKNNPDFHDKDLYAMDMEMTQQNRLYTPQLNHITLNFPSLA 740

  Fly   515 LLQGRHLYQDDRYFCNKSSLAAEGRNCERELCECVNVMRLPAYRPLEMVVAN----YLDSTHPFH 575
            ||..|...:|.. |||::||..:|.:|.:|.|:|.:|:::|....:||::.:    |. :.||||
  Fly   741 LLPSRSQLKDSD-FCNETSLMDQGIDCRQEFCKCHHVLQVPLGAVVEMIIVDEGFQYY-ANHPFH 803

  Fly   576 IHGFTFRLVGQGVLGNLNDLRNIQELDRRGRLPRLSEDSAAVAKDTVQIPGQGYIIVRFISNNPG 640
            :||..||::|...||....:..|::||:...|.| :.|:..| ||||.||..||.|:||.::|||
  Fly   804 LHGNAFRVMGLERLGENVTVEMIKQLDQFNLLKR-NLDNPPV-KDTVTIPDGGYTIIRFEASNPG 866

  Fly   641 FWLYHCHVEAHAVQGMVAVLKIGEDHQMKNIP 672
            :||:|||:|.||..||..|.|:|.|.||..:|
  Fly   867 YWLFHCHIEFHAEIGMALVFKVGNDDQMVPVP 898

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mco3	NP_651441.1	CuRO_1_tcLCC2_insect_like	149..252	CDD:259927	54/103 (52%)
		laccase	151..656	CDD:274556	202/607 (33%)
		CuRO_2_tcLCC_insect_like	270..408	CDD:259951	58/210 (28%)
Mco1	NP_609287.3	VWC	150..212	CDD:214564	9/38 (24%)
		CuRO_1_tcLCC2_insect_like	293..397	CDD:259927	54/103 (52%)
		CuRO_2_tcLCC_insect_like	415..626	CDD:259951	58/210 (28%)
		CuRO_3_tcLLC2_insect_like	728..897	CDD:259972	71/172 (41%)