Protein Alignment Mco3 and F8

DIOPT Version :10

• Sequence 1: NP_651441.1
• Gene: Mco3 / 43134
• FlyBaseID: FBgn0039387
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_032003.2
• Gene: F8 / 14069
• MGIID: 88383
• Length: 2319
• Species: Mus musculus
• Alignment Length: 717
• Identity: 128/717 - (17%)
• Similarity: 213/717 - (29%)
• Gaps: 300/717 - (41%)

  Fly   164 GPSIELCENDTVVVDVLNYLSEPTTMHWHGVHMHRTPEMDGAPFITQYPLQPGEVQRHEFKVDRS 228
            ||:|....:||||:.:.|..|.|.::|..||...:..|.|      :|..|..::::.:.||...
Mouse    93 GPTIWTEVHDTVVITLKNMASHPVSLHAVGVSYWKASEGD------EYEDQTSQMEKEDDKVFPG 151

  Fly   229 GS---LW-------------------YHSHVGWQRGF--GVAGAFVV-RQTSQENQHSQ-LYDYD 267
            .|   :|                   |.|||...:..  |:.||.:| ::.|...:.:| ||.:
Mouse   152 ESHTYVWQVLKENGPMASDPPCLTYSYMSHVDLVKDLNSGLIGALLVCKEGSLSKERTQMLYQF- 215

  Fly   268 LVEHTLMIQDIFYEYNLQDVRNILVNGKG-----RNHLSQLPDNDNRHRYERLRVTPGYRYRMRV 327
                 :::..:|.|            ||.     .:..:|..|:.:...:.::....||..|.
Mouse   216 -----VLLFAVFDE------------GKSWHSETNDSYTQSMDSASARDWPKMHTVNGYVNRS-- 261

  Fly   328 ILNGIANCPVE------------------------FSIEQHRLLMISTDGNDIEPV--------L 360
             |.|:..|..:                        |.:..||...:     :|.|:        |
Mouse   262 -LPGLIGCHRKSVYWHVIGMGTTPEIHSIFLEGHTFFVRNHRQASL-----EISPITFLTAQTLL 320

  Fly   361 AD-GFFL----TSAERFD---------------------------------------FVLE---- 377
            .| |.||    .|:.:.|                                       |.|:
Mouse   321 IDLGQFLLFCHISSHKHDGMEAYVKVDSCPEESQWQKKNNNEEMEDYDDDLYSEMDMFTLDYDSS 385

  Fly   378 --------ANQYKKNYWIRIKGYEQCENRNIYQGAVLSYRGSARSE-LPQGDILDKPSSRAADED 433
                    |.:|.|. ||.....|: |:.:.......|..||.:|: |..|.  .:...:.....
Mouse   386 PFIQIRSVAKKYPKT-WIHYISAEE-EDWDYAPSVPTSDNGSYKSQYLSNGP--HRIGRKYKKVR 446

  Fly   434 LILVNDFRFKPANSTAISSLRQSLDKDN---------NVGTVAL---RSVDPVPWTRYTKFLTHY 486
            .|...|..||         .|:::..::         .||...|   ::....|:..|...:|..
Mouse   447 FIAYTDETFK---------TRETIQHESGLLGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDV 502

  Fly   487 SSFGSRTAPNGEVLFQISDISYNSPGISLLQGRHLYQD----------DRYF------------- 528
            |...:|..|.|  :..:.|:..:...|...:.....:|          .||:
Mouse   503 SPLHARRLPRG--IKHVKDLPIHPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFINPERDLASG 565

  Fly   529 -------CNKSSLAAEG-------------------------RNCEREL------------CECV 549
                   |.|.|:...|                         .|.:|.|            .:..
Mouse   566 LIGPLLICYKESVDQRGNQMMSDKRNVILFSIFDENQSWYITENMQRFLPNAAKTQPQDPGFQAS 630

  Fly   550 NVMRL---PAYRPLEMVVANYLDSTHPFHI--------------HGFTFRLVGQGVLGNLNDLRN 597
            |:|..   ..:..||:.|.  |.....:||              .|:||:
Mouse   631 NIMHSINGYVFDSLELTVC--LHEVAYWHILSVGAQTDFLSIFFSGYTFK--------------- 678

  Fly   598 IQELDRRGRLPRLSEDSAAVAKDTVQI-PGQGYIIVRFIS-NNPGFWLYHCHVEAHAVQGMVAVL 660
                            ...|.:||:.: |..|..:  |:| .|||.|:..||......:||.|:|
Mouse   679 ----------------HKMVYEDTLTLFPFSGETV--FMSMENPGLWVLGCHNSDFRKRGMTALL 725

  Fly   661 KI 662
            |:
Mouse   726 KV 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mco3	NP_651441.1	CuRO_1_tcLCC2_insect_like	149..252	CDD:259927	29/112 (26%)
		laccase	151..656	CDD:274556	123/709 (17%)
		CuRO_2_tcLCC_insect_like	270..408	CDD:259951	33/230 (14%)
F8	NP_032003.2	Cupredoxin	22..202	CDD:473140	29/114 (25%)
		Cupredoxin	212..346	CDD:473140	26/159 (16%)
		CuRO_3_FVIII_like	399..575	CDD:259889	32/190 (17%)
		Cupredoxin	588..730	CDD:473140	32/175 (18%)
		B	760..1640
		rpoC2	<1134..>1509	CDD:214368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1530..1549
		Cupredoxin	1684..1848	CDD:473140
		Cupredoxin	1860..2003	CDD:473140
		FA58C	2011..2155	CDD:238014
		FA58C	2164..2312	CDD:238014