Protein Alignment SppL and YPF1

DIOPT Version :10

• Sequence 1: NP_001163740.1
• Gene: SppL / 43128
• FlyBaseID: FBgn0039381
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_012822.1
• Gene: YPF1 / 853761
• SGDID: S000001583
• Length: 587
• Species: Saccharomyces cerevisiae
• Alignment Length: 504
• Identity: 117/504 - (23%)
• Similarity: 190/504 - (37%)
• Gaps: 162/504 - (32%)

  Fly    32 YRELHWTVSSVMDSSRV----STCLISMLLIVYGSFRSL----------------------NIEQ 70
            ||..|.....|...|.|    :..||:..|:|.|||.|:                      :::.
Yeast    63 YRVAHKITHLVESHSLVFNYATLVLIASALVVIGSFTSISSIPFTALPPTREHSLFDPTDFDVDH 127

  Fly    71 EA----REREQKKRNESMTNLLTGEPVEKEPNLYFTADKFATLDTMHALCLPLGASISLLIMFFF 131
            :.    ||.::.|:             :|:.:..|    |..:|..||:.|||.:..:||.::|.
Yeast   128 DCHVIYRENDEDKK-------------KKKKSKRF----FDMMDEKHAIILPLTSGCTLLALYFV 175

  Fly   132 FDSMQLLFAVCTAIIATVALAFLLLP----------------------------MCQYIIRPCTD 168
            ...:.|.:......|....:..|.:|                            :.:|.:....|
Yeast   176 IKKLHLNWLKYVVKILNFNITLLNIPAGTFVYSYFLNSLFRNLSHLASWNPLVVLPRYRVTIADD 240

  Fly   169 GKRFS--FGFCGR--------------------------------------------------FT 181
            .:..:  .||...                                                  ..
Yeast   241 NEDLNKIGGFVTNLNYKDGLTNSVVHKKTLDEIEKDHWMKHFYRRELVEPKDIKSKRQISNMYLN 305

  Fly   182 AAELFSFTLS-VSIVCIWVLTGHWLLMDAMGMGLCVAFIAFVRLPSLKVSTLLLTGLLIYDVFWV 245
            :|.:.||.|| ||.|..::....||:.:|:.|.:.:..||.::|.:||...|:|..|..||:
Yeast   306 SALIVSFVLSIVSTVYFYLSPNDWLISNAVSMNMAIWSIAQLKLKNLKSGALILIALFFYDI--- 367

  Fly   246 FLSSYIFSTNVMVKVATRPADNPVGIVARKLHLGGIVRDTPKLNLPGKLVFPSLHNTGHFSMLGL 310
               .::|.|:|||.|||. .|.||                 ||:||.|  |.:..|..:||:|||
Yeast   368 ---CFVFGTDVMVTVATN-LDIPV-----------------KLSLPVK--FNTAQNNFNFSILGL 409

  Fly   311 GDVVMPGLLLCFVLRYDAYKKAQGVTSDPT---LSPPRGVGSRLTYFHCSLLGYFLGLLTATVSS 372
            ||:.:||:.:....:||.:|  ..:..|.|   ......||.   ||..:::.|...|::|.||.
Yeast   410 GDIALPGMFIAMCYKYDIWK--WHLDHDDTEFHFLNWSYVGK---YFITAMVSYVASLVSAMVSL 469

  Fly   373 EVFKAAQPALLYLVPFTLLPLLLMAYLKGDLRRMWSEPFIAQQPSKQLE 421
            .:|..|||||||:||..|:..:|:|....|.::.|:..:...:..|.|:
Yeast   470 SIFNTAQPALLYIVPSLLISTILVACWNKDFKQFWNFQYDTIEVDKSLK 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SppL	NP_001163740.1	Peptidase_A22B	102..413	CDD:282158	96/394 (24%)
YPF1	NP_012822.1	Peptidase_A22B	148..510	CDD:282158	97/396 (24%)