DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SppL and SPPL2

DIOPT Version :9

Sequence 1:	NP_001163740.1	Gene:	SppL / 43128	FlyBaseID:	FBgn0039381	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_564815.1	Gene:	SPPL2 / 842673	AraportID:	AT1G63690	Length:	540	Species:	Arabidopsis thaliana

Alignment Length:	391	Identity:	108/391 - (27%)
Similarity:	175/391 - (44%)	Gaps:	81/391 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 MDSSRVSTCLISMLLIVYGSFRSLNIEQEAREREQKKRNESMTNLLTGEPVEKEPNLYFTADKFA 107
            :|.:.|...|:::..|:..|:.|....:||.....|         |..:.:::.||.........
plant   192 VDVAEVFLWLMAIGTILCASYWSAWSAREAAIEHDK---------LLKDAIDEIPNTNDGGSGVV 247

  Fly   108 TLDTMHALCLPLGASISLLIM-----FFFFDSMQLLFAVCTAIIATVALAFLLLPMCQ-----YI 162
            .::::.|:...:.||..|:|:     ::|.:.:.::|.:.........|..||....|     |:
plant   248 EINSISAIFFVVLASGFLVILYKLMSYWFVELLVVVFCIGGVEGLQTCLVALLSRWFQRAADTYV 312

  Fly   163 IRPCTDGKRFSFGFCGRFTAAELFSFTLSVSIVCI-----W-VLTGH---WLLMDAMGMGLCVAF 218
            ..|          |.|     .:...||:||..||     | |...|   |:..|.:|:.|.:..
plant   313 KVP----------FLG-----PISYLTLAVSPFCIVFAVLWAVYRVHSFAWIGQDVLGIALIITV 362

  Fly   219 IAFVRLPSLKVSTLLLTGLLIYDVFWVFLSSYIFSTNVMVKVATRPADNPVGIVARKLHLGGIVR 283
            :..|.:|:|||.|:||:...:||:||||:|..:|..:||:.||........||
plant   363 LQIVHVPNLKVGTVLLSCAFLYDIFWVFVSKKLFHESVMIVVARGDKSGEDGI------------ 415

  Fly   284 DTPKLNLPGKLVFPSLHNT-GHFSMLGLGDVVMPGLLLCFVLRYDAYKKAQGVTSDPTLSPPRGV 347
                   |..|..|.:.:. |.:|::|.||:::||||:.|.||||       ..::.||
plant   416 -------PMLLKIPRMFDPWGGYSIIGFGDILLPGLLIAFALRYD-------WLANKTL------ 460

  Fly   348 GSRLTYFHCSLLGYFLGLLTATVSSEVFKA-AQPALLYLVPFTLLPLLLMAYLKGDLRRMWS--E 409
              |..||..:::.|.||||...|:..:... .||||||:|||||..:|.:|..:.||..:|:  |
plant   461 --RTGYFIWAMVAYGLGLLITYVALNLMDGHGQPALLYIVPFTLGTMLTLARKRDDLWILWTKGE 523

  Fly   410 P 410
            |
plant   524 P 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SppL	NP_001163740.1	Peptidase_A22B	102..413	CDD:282158	96/332 (29%)
SPPL2	NP_564815.1	PA_GO-like	46..184	CDD:239047
SPPL2	NP_564815.1	Peptidase_A22B	245..525	CDD:282158	96/329 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810