Protein Alignment SppL and sppl2

DIOPT Version :10

• Sequence 1: NP_001163740.1
• Gene: SppL / 43128
• FlyBaseID: FBgn0039381
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_001038709.2
• Gene: sppl2 / 325540
• ZFINID: ZDB-GENE-030131-4265
• Length: 555
• Species: Danio rerio
• Alignment Length: 415
• Identity: 106/415 - (25%)
• Similarity: 185/415 - (44%)
• Gaps: 86/415 - (20%)

  Fly    30 GEYRE--LHWTVSSVMDSSRVSTCLISMLLIVYGSFRSLNIEQEAREREQKKRNESMTNLLTGEP 92
            ||.|:  ::.....|:|.:.|...|:::..:..|.:.:.:  ::.::|..|.:.:........|.
Zfish   149 GEKRQVAMYAPNEPVVDYNMVLIFLMAVGTVALGGYWAGS--RDIKKRYMKHKRDDGAEKQDEET 211

  Fly    93 VEKEPNLYFTADKFATLDTMHALCLPLGASISLLIMFFFFDSMQLLFAVCTAIIAT-VALAFLLL 156
            |:..|.:               :|:.:....|:|::.:||....:...:.|..:|: |:|...|.
Zfish   212 VDVTPIM---------------ICVFVVMCCSMLVLLYFFYDQLVYMTIATFCLASAVSLYSCLW 261

  Fly   157 PMCQYIIRPCTDGKRFSFGFC-------------GRFTAAELFSFTLSVSIVCIWVLTGH----- 203
            |..          :|..||.|             .:.....|.:|.:.||:.  |.:..:
Zfish   262 PFV----------RRIPFGKCRIPENNLPYCHKRPQVRMLILSAFCIGVSVT--WGVFRNEDQWA 314

  Fly   204 WLLMDAMGMGLCVAFIAFVRLPSLKVSTLLLTGLLIYDVFWVFLSSYIFST--NVMVKVATRPAD 266
            |:|.||:|:..|:..:..:|||:.|..||||..|.:||||:||::..:..:  ::||:||..|:|
Zfish   315 WILQDALGIAFCLYMLKTIRLPTFKACTLLLVVLFVYDVFFVFITPLLTKSGESIMVEVAAGPSD 379

  Fly   267 NPVGIVARKLHLGGIVRDTPKLNLPGKLVFPSLHNTGHFSMLGLGDVVMPGLLLCFVLRYDAYKK 331
            :.   ...||.:   |...|:||..     |.:.....||:||.||:::||||:.:..|:|...:
Zfish   380 SS---THEKLPM---VLKVPRLNSS-----PLVLCDRPFSLLGFGDILVPGLLVAYCHRFDILMQ 433

  Fly   332 AQGVTSDPTLSPPRGVGSRLTYFHCSLLGYFLGLLTATVSSEVFKAAQPALLYLVPFTLLPLLLM 396
            ...:                 ||....:||.:|||...|:..:.:..|||||||||.|||..|.:
Zfish   434 TSQI-----------------YFLACTIGYGIGLLITFVALTLMQMGQPALLYLVPCTLLTSLAV 481

  Fly   397 AYLKGDLRRMWS------EPFIAQQ 415
            |..:.:|...|:      .|.|.:|
Zfish   482 ALWRKELPLFWTGSGFVPPPIIMEQ 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SppL	NP_001163740.1	Peptidase_A22B	102..413	CDD:282158	91/337 (27%)
sppl2	NP_001038709.2	PA_hSPPL_like	37..156	CDD:239044	3/6 (50%)
		Peptidase_A22B	206..497	CDD:282158	93/345 (27%)