Protein Alignment SppL and imp-1

DIOPT Version :10

• Sequence 1: NP_001163740.1
• Gene: SppL / 43128
• FlyBaseID: FBgn0039381
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_001021025.1
• Gene: imp-1 / 172684
• WormBaseID: WBGene00007979
• Length: 662
• Species: Caenorhabditis elegans
• Alignment Length: 421
• Identity: 107/421 - (25%)
• Similarity: 189/421 - (44%)
• Gaps: 83/421 - (19%)

  Fly    44 DSSRVSTCLISMLLIVYGSFRSLNIEQEAREREQKK---RNESMTNLLTGEPVEKEPNLYFTADK 105
            |:|.....:|||..:..|...:.|     |.|..|.   .::|:.:..:....:.|...:.  |:
 Worm   231 DASFAIIWMISMTCVAGGGIWAFN-----RHRAGKDVTLASQSVDDDTSSPSNDSETKGFL--DR 288

  Fly   106 FATLDTMHALCLPLGASISLLIM-FFFFDSMQLLFAVCTAIIATVALAFLL---LPMCQYIIRPC 166
            |..:.|   :||.:.....:|:: :||...:.:.|.:...|..|.:|...:   |...:::....
 Worm   289 FGGIIT---ICLMMTTLCGVLLLGYFFRPVLVIFFNIFLVIFGTCSLYGCIRGFLSNFKFVGHRW 350

  Fly   167 TDGKRFSFGFCG----RFTAAELFSFTLSVSIVCIWVLTGH----WLLMDAMGMGLCVAFIAFVR 223
            .:.|...|..||    ::..:|.|...:.:|....|.:...    ::|:|.:.|.||:..:..:|
 Worm   351 YNAKMEWFPTCGGRIHQYKYSEAFIGIICLSFCVTWFIIRRQPYAFILLDVINMALCMHVLKCLR 415

  Fly   224 LPSLKVSTLLLTGLLIYDVFWVFLSSYIFSTN---VMVKVATRPADNPVGIVARKLHLGGIVRDT 285
            |||||..::|:..:.:||.|.||.:.|: :||   ||::|||     .:...|:..:.|..|...
 Worm   416 LPSLKWISILMLCMFVYDAFMVFGTPYM-TTNGCSVMLEVAT-----GLSCAAKGKNKGYPVPPI 474

  Fly   286 PKLNLPGKLVFPSLHNTGH-----------------FSMLGLGDVVMPGLLL--CFVLRYDAYKK 331
            .:.::|.|  ||.|....|                 |::|||||:||||.|:  ||.:
 Worm   475 EQESVPEK--FPMLMQVAHFNPMNECLDMEIELGFQFTILGLGDIVMPGYLVAHCFTM------- 530

  Fly   332 AQGVTSDPTLSPPRGVGS--RLTYFHCSLLGYFLGLLTATVSSEVFKAAQPALLYLVPFTLLPLL 394
                         .|...  ||.|...|::||.:||:...::..:.|.|||||:||||.||.|::
 Worm   531 -------------NGFSERVRLIYGFISVVGYGIGLIVTFLALALMKTAQPALIYLVPSTLFPII 582

  Fly   395 LMAYLKGDLRRMWS------EPFIAQQPSKQ 419
            ::|..:|:..::|:      .|.::.:...|
 Worm   583 MLALCRGEFLKIWNGVPVECSPLVSDRNDLQ 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SppL	NP_001163740.1	Peptidase_A22B	102..413	CDD:282158	94/352 (27%)
imp-1	NP_001021025.1	Peptidase_A22B	275..601	CDD:282158	94/358 (26%)