DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5890 and Duox2

DIOPT Version :9

Sequence 1:	NP_001356889.1	Gene:	CG5890 / 43126	FlyBaseID:	FBgn0039380	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	NP_077055.2	Gene:	Duox2 / 79107	RGDID:	628761	Length:	1517	Species:	Rattus norvegicus

Alignment Length:	132	Identity:	35/132 - (26%)
Similarity:	64/132 - (48%)	Gaps:	22/132 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 LYAHYVFKAFDVNCNGAISFRDLLVTLSTLLRGSVYERLRWTFKLYDLNGDGRISRGELSEIILA 143
            ::...:|...|.:.||.||||:.|..|...::||..::.|..|.:|||:|:|.:|:.|...::.:
  Rat   822 MFVESMFSLADKDGNGYISFREFLDILVVFMKGSPQDKSRLMFTMYDLDGNGFLSKEEFFTMMRS 886

  Fly   144 IHELMGRRPHQPEDDRKARDQ----VDRVFRKLDLNQDGIITIEEFLEACLKDDLVTRSLQMFDN 204
            ..|:        .::..::||    |:.:||:........:|.|:| ...|:|         .|:
  Rat   887 FIEI--------SNNCLSKDQLAEVVESMFRESGFQDKEELTWEDF-HFMLRD---------HDS 933

  Fly   205 DL 206
            ||
  Rat   934 DL 935

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5890	NP_001356889.1	FRQ1	29..192	CDD:227455	31/116 (27%)
Duox2	NP_077055.2	Peroxidase-like, mediates peroxidase activity. /evidence=ECO:0000250	30..596
		dual_peroxidase_like	38..594	CDD:188652
		FRQ1	<719..856	CDD:227455	11/33 (33%)
		EFh	824..885	CDD:238008	21/60 (35%)
		EFh	861..919	CDD:238008	15/65 (23%)
		Interaction with TXNDC11. /evidence=ECO:0000250	960..1214
		Ferric_reduct	1057..1201	CDD:396386
		NOX_Duox_like_FAD_NADP	1243..1517	CDD:99783
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910