DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5890 and Kcnip1

DIOPT Version :9

Sequence 1:	NP_001356889.1	Gene:	CG5890 / 43126	FlyBaseID:	FBgn0039380	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	XP_017170240.1	Gene:	Kcnip1 / 70357	MGIID:	1917607	Length:	249	Species:	Mus musculus

Alignment Length:	199	Identity:	100/199 - (50%)
Similarity:	141/199 - (70%)	Gaps:	5/199 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 EEVVYELEHTRVPKPIPVALEDLCRQTKFTKQEIRVMYRGFKTECPEGVVHEDCFKDIYAKFFPH 74
            :::..|||.|.|... |..||.|..||.|||:|::|:|||||.|||.|||:|:.||.|||:||||
Mouse    50 DKIEDELEMTMVCHR-PEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPH 113

  Fly    75 GNSSLYAHYVFKAFDVNCNGAISFRDLLVTLSTLLRGSVYERLRWTFKLYDLNGDGRISR----G 135
            |::|.||||:|.|||....|::.|.|.:..||.||||:|:|:|||||.|||:|.||.|::    .
Mouse   114 GDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEVPFQ 178

  Fly   136 ELSEIILAIHELMGRRPHQPEDDRKARDQVDRVFRKLDLNQDGIITIEEFLEACLKDDLVTRSLQ 200
            |:.:|:.||:::||:..:....:...|..||..|:|:|.|:|||:|::||||:|.:||.:.||||
Mouse   179 EMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQ 243

  Fly   201 MFDN 204
            :|.|
Mouse   244 LFQN 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5890	NP_001356889.1	FRQ1	29..192	CDD:227455	86/166 (52%)
Kcnip1	XP_017170240.1	FRQ1	68..238	CDD:227455	88/169 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833425
Domainoid	1	1.000	96	1.000	Domainoid score	I7294
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H22824
Inparanoid	1	1.050	212	1.000	Inparanoid score	I3634
Isobase	1	0.950	-	0	Normalized mean entropy	S788
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606780at33208
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	1	1.000	-	-		otm42579
orthoMCL	1	0.900	-	-		OOG6_101448
Panther	1	1.100	-	-	O	PTHR23055
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5210
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.880